Literature DB >> 26401056

CHALLENGES FOR IMPLEMENTING A PTSD PREVENTIVE GENOMIC SEQUENCING PROGRAM IN THE U.S. MILITARY.

Gabriel Lázaro-Muñoz1, Eric T Juengst2.   

Abstract

There is growing interest in using the quickly developing field of genomics to contribute to military readiness and effectiveness. Specifically, influential military advisory panels have recommended that the U.S. military apply genomics to help treat, prevent, or minimize the risk for post-traumatic stress disorder (PTSD) among service members. This article highlights some important scientific, legal, and ethical challenges regarding the development and deployment of a preventive genomic sequencing (PGS) program to predict the risk of PTSD among military service members.

Entities:  

Year:  2015        PMID： 26401056      PMCID： PMC4577019     

Source DB:  PubMed          Journal:  Case West Reserve J Int Law        ISSN： 0008-7254


  38 in total

1.  Posttraumatic stress symptoms among National Guard soldiers deployed to Iraq: associations with parenting behaviors and couple adjustment.

Authors:  Abigail H Gewirtz; Melissa A Polusny; David S DeGarmo; Anna Khaylis; Christopher R Erbes
Journal:  J Consult Clin Psychol       Date:  2010-10

2.  Currents in contemporary ethics. GINA, the ADA, and genetic discrimination in employment.

Authors:  Mark A Rothstein
Journal:  J Law Med Ethics       Date:  2008       Impact factor: 1.718

3.  From candidate genes to genome-wide association: the challenges and promise of posttraumatic stress disorder genetic studies.

Authors:  Karestan C Koenen; Laramie E Duncan; Israel Liberzon; Kerry J Ressler
Journal:  Biol Psychiatry       Date:  2013-11-01       Impact factor: 13.382

4.  PTSD in the U.S. military, and the politics of prevalence.

Authors:  Michael P Fisher
Journal:  Soc Sci Med       Date:  2014-06-02       Impact factor: 4.634

Review 5.  Genome-scale neurogenetics: methodology and meaning.

Authors:  Steven A McCarroll; Guoping Feng; Steven E Hyman
Journal:  Nat Neurosci       Date:  2014-05-27       Impact factor: 24.884

6.  Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication.

Authors:  Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Kathleen R Merikangas; Ellen E Walters
Journal:  Arch Gen Psychiatry       Date:  2005-06

Review 7.  Biological studies of post-traumatic stress disorder.

Authors:  Roger K Pitman; Ann M Rasmusson; Karestan C Koenen; Lisa M Shin; Scott P Orr; Mark W Gilbertson; Mohammed R Milad; Israel Liberzon
Journal:  Nat Rev Neurosci       Date:  2012-10-10       Impact factor: 34.870

8.  Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study.

Authors:  Murray B Stein; Kerry L Jang; Steven Taylor; Philip A Vernon; W John Livesley
Journal:  Am J Psychiatry       Date:  2002-10       Impact factor: 18.112

9.  New onset and persistent symptoms of post-traumatic stress disorder self reported after deployment and combat exposures: prospective population based US military cohort study.

Authors:  Tyler C Smith; Margaret A K Ryan; Deborah L Wingard; Donald J Slymen; James F Sallis; Donna Kritz-Silverstein
Journal:  BMJ       Date:  2008-01-15

10.  Biological insights from 108 schizophrenia-associated genetic loci.

Authors: 
Journal:  Nature       Date:  2014-07-22       Impact factor: 49.962
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