Literature DB >> 26400814

Role of Circulating Cell-Free DNA in Cancers.

Raghu Aarthy1, Samson Mani1, Sridevi Velusami2, Shirley Sundarsingh3, Thangarajan Rajkumar4.   

Abstract

Liquid biopsy is a term used to describe non-invasive tests, which provide information about disease conditions through analysis of circulating cell-free DNA and circulating tumor cells from peripheral blood samples. In patients with cancer, the concentration of cell-free DNA increases, and structural, sequence, and epigenetic changes to DNA can be observed through the disease process and during therapy. Furthermore, cell-free DNA released by the tumor contains the same variants as those in the tumor cells. Therefore, cell-free DNA allows non-invasive assessment of cancer in real time. This review summarizes the origin of cell-free DNA, recent advancements in the detection of cell-free DNA, a possible role in metastasis, and its importance as a non-invasive diagnostic assay for cancer.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26400814     DOI： 10.1007/s40291-015-0167-y

Source DB:  PubMed          Journal:  Mol Diagn Ther        ISSN： 1177-1062            Impact factor:   4.074


  111 in total

Review 1.  Basic principles of real-time quantitative PCR.

Authors:  Manit Arya; Iqbal S Shergill; Magali Williamson; Lyndon Gommersall; Neehar Arya; Hitendra R H Patel
Journal:  Expert Rev Mol Diagn       Date:  2005-03       Impact factor: 5.225

2.  [Not Available].

Authors:  P MANDEL; P METAIS
Journal:  C R Seances Soc Biol Fil       Date:  1948-02

Review 3.  DNA methylation and gene silencing in cancer.

Authors:  Stephen B Baylin
Journal:  Nat Clin Pract Oncol       Date:  2005-12

4.  Intragenic DNA methylation concomitant with repression of ATP4B and ATP4A gene expression in gastric cancer is a potential serum biomarker.

Authors:  Uthandaraman Mahalinga Raja; Gopisetty Gopal; Thangarajan Rajkumar
Journal:  Asian Pac J Cancer Prev       Date:  2012

5.  Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer.

Authors:  Hsueh-Wei Chang; Shing M Lee; Steven N Goodman; Gad Singer; Sarah K R Cho; Lori J Sokoll; Fredrick J Montz; Richard Roden; Zhen Zhang; Daniel W Chan; Robert J Kurman; Ie-Ming Shih
Journal:  J Natl Cancer Inst       Date:  2002-11-20       Impact factor: 13.506

6.  Quantitative analysis of circulating methylated DNA as a biomarker for hepatocellular carcinoma.

Authors:  K C Allen Chan; Paul B S Lai; Tony S K Mok; Henry L Y Chan; Chunming Ding; S W Yeung; Y M Dennis Lo
Journal:  Clin Chem       Date:  2008-07-24       Impact factor: 8.327

7.  Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.

Authors:  Sumitra Mohan; Ellen Heitzer; Peter Ulz; Ingrid Lafer; Sigurd Lax; Martina Auer; Martin Pichler; Armin Gerger; Florian Eisner; Gerald Hoefler; Thomas Bauernhofer; Jochen B Geigl; Michael R Speicher
Journal:  PLoS Genet       Date:  2014-03-27       Impact factor: 6.020

8.  Detection of EGFR mutations in the plasma of patients with lung adenocarcinoma for real-time monitoring of therapeutic response to tyrosine kinase inhibitors?

Authors:  Marie Marcq; Audrey Vallée; Acya Bizieux; Marc G Denis
Journal:  J Thorac Oncol       Date:  2014-07       Impact factor: 15.609

9.  Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients.

Authors:  Aleksandra Majchrzak-Celińska; Jarosław Paluszczak; Robert Kleszcz; Marta Magiera; Anna-Maria Barciszewska; Stanisław Nowak; Wanda Baer-Dubowska
Journal:  J Appl Genet       Date:  2013-05-10       Impact factor: 3.240

10.  First-line gefitinib in Caucasian EGFR mutation-positive NSCLC patients: a phase-IV, open-label, single-arm study.

Authors:  J-Y Douillard; G Ostoros; M Cobo; T Ciuleanu; R McCormack; A Webster; T Milenkova
Journal:  Br J Cancer       Date:  2013-11-21       Impact factor: 7.640
View more
  22 in total

Review 1.  Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.

Authors:  Karen-Lise G Spindler; Anders K Boysen; Niels Pallisgård; Julia S Johansen; Josep Tabernero; Morten M Sørensen; Benny V Jensen; Torben F Hansen; David Sefrioui; Rikke F Andersen; Ivan Brandslund; Anders Jakobsen
Journal:  Oncologist       Date:  2017-08-04

2.  Loop-Mediated Isothermal Amplification for Detection of the 5.8S Ribosomal Ribonucleic Acid Internal Transcribed Spacer 2 Gene Found in Trypanosoma brucei gambiense.

Authors:  Olga V Nikolskaia; Oriel M M Thekisoe; J Stephen Dumler; Dennis J Grab
Journal:  Am J Trop Med Hyg       Date:  2016-06-06       Impact factor: 2.345

3.  Plasma DNA methylation marker and hepatocellular carcinoma risk prediction model for the general population.

Authors:  Hui-Chen Wu; Hwai-I Yang; Qiao Wang; Chien-Jen Chen; Regina M Santella
Journal:  Carcinogenesis       Date:  2017-10-01       Impact factor: 4.944

Review 4.  Saliva Diagnostics.

Authors:  Taichiro Nonaka; David T W Wong
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2022-06-13       Impact factor: 12.400

5.  Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer.

Authors:  Dimitrios Matthaios; Ioanna Balgkouranidou; Anastasios Karayiannakis; Helen Bolanaki; Nikolaos Xenidis; Kyriakos Amarantidis; Leonidas Chelis; Konstantinos Romanidis; Aikaterini Chatzaki; Evi Lianidou; Grigorios Trypsianis; Stylianos Kakolyris
Journal:  Oncol Lett       Date:  2016-06-01       Impact factor: 2.967

Review 6.  Saliva-Exosomics in Cancer: Molecular Characterization of Cancer-Derived Exosomes in Saliva.

Authors:  Taichiro Nonaka; David T W Wong
Journal:  Enzymes       Date:  2017-10-09

Review 7.  Metastatic gynecologic malignancies: advances in treatment and management.

Authors:  John K Chan; Stephanie Chow; Subasish Bhowmik; Amandeep Mann; Daniel S Kapp; Robert L Coleman
Journal:  Clin Exp Metastasis       Date:  2018-06-21       Impact factor: 5.150

Review 8.  The role of extracellular DNA (exDNA) in cellular processes.

Authors:  Ileana J Fernández-Domínguez; Joaquin Manzo-Merino; Lucia Taja-Chayeb; Alfonso Dueñas-González; Enrique Pérez-Cárdenas; Catalina Trejo-Becerril
Journal:  Cancer Biol Ther       Date:  2021-04-16       Impact factor: 4.742

Review 9.  When Tissue is an Issue the Liquid Biopsy is Nonissue: A Review.

Authors:  July Rodríguez; Jenny Avila; Christian Rolfo; Alejandro Ruíz-Patiño; Alessandro Russo; Luisa Ricaurte; Camila Ordóñez-Reyes; Oscar Arrieta; Zyanya Lucia Zatarain-Barrón; Gonzalo Recondo; Andrés F Cardona
Journal:  Oncol Ther       Date:  2021-03-10

10.  Increased level and fragmentation of plasma circulating cell-free DNA are diagnostic and prognostic markers for renal cell carcinoma.

Authors:  Yoshiyuki Yamamoto; Motohide Uemura; Kosuke Nakano; Yujiro Hayashi; Cong Wang; Yu Ishizuya; Toshiro Kinouchi; Takuji Hayashi; Kyosuke Matsuzaki; Kentaro Jingushi; Taigo Kato; Atsunari Kawashima; Takeshi Ujike; Akira Nagahara; Kazutoshi Fujita; Ryoichi Imamura; Norio Nonomura
Journal:  Oncotarget       Date:  2018-04-17
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.