Literature DB >> 26400698

Retention in pre-antiretroviral treatment care in a district of Karnataka, India: how well are we doing?

D Shankar1, A M V Kumar2, B Rewari3, S Kumar4, S Shastri5, S Satyanarayana2, R Ananthakrishnan6, S B Nagaraja7, M Devi1, N Bhargava1, M Das8, R Zachariah8.   

Abstract

SETTING: Antiretroviral treatment (ART) Centre in Tumkur district of Karnataka State, India. There is no published information about pre-ART loss to follow-up from India.
OBJECTIVE: To assess the proportion lost to follow-up (defined as not visiting the ART Centre within 1 year of registration) and associated socio-demographic and immunological variables.
DESIGN: Retrospective cohort study involving a review of medical records of adult HIV-infected persons (aged ⩾15 years) registered in pre-ART care during January 2010-June 2012.
RESULTS: Of 3238 patients registered, 2519 (78%) were eligible for ART, while 719 (22%) were not. Four of the latter were transferred out; the remaining 715 individuals were enrolled in pre-ART care, of whom 290 (41%) were lost to follow-up. Factors associated with loss to follow-up on multivariate analysis included age group ⩾45 years, low educational level, not being married, World Health Organization Stage III or IV and rural residence.
CONCLUSION: About four in 10 individuals in pre-ART care were lost to follow-up within 1 year of registration. This needs urgent attention. Routine cohort analysis in the national programme should include those in pre-ART care to enable improved review, monitoring and supervision. Further qualitative research to ascertain reasons for loss to follow-up is required to design future interventions.

Entities:  

Keywords:  ART centre; India; NACP; loss to follow-up; operational research; pre-ART

Year:  2014        PMID: 26400698      PMCID: PMC4533510          DOI: 10.5588/pha.14.0073

Source DB:  PubMed          Journal:  Public Health Action        ISSN: 2220-8372


  19 in total

1.  Estimating the relative risk in cohort studies and clinical trials of common outcomes.

Authors:  Louise-Anne McNutt; Chuntao Wu; Xiaonan Xue; Jean Paul Hafner
Journal:  Am J Epidemiol       Date:  2003-05-15       Impact factor: 4.897

2.  Why ethics is indispensable for good-quality operational research.

Authors:  M Edginton; D Enarson; R Zachariah; T Reid; S Satyanarayana; K Bissell; S G Hinderaker; T Harries
Journal:  Public Health Action       Date:  2012-03-21

3.  Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in Africa.

Authors:  Elvin H Geng; David V Glidden; Nneka Emenyonu; Nicolas Musinguzi; Mwebwesa Bosco Bwana; Torsten B Neilands; Winnie Muyindike; Constantin T Yiannoutsos; Steven G Deeks; David R Bangsberg; Jeffrey N Martin
Journal:  Trop Med Int Health       Date:  2010-06       Impact factor: 2.622

Review 4.  Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions.

Authors:  Elvin H Geng; Denis Nash; Andrew Kambugu; Yao Zhang; Paula Braitstein; Katerina A Christopoulos; Winnie Muyindike; Mwebesa Bosco Bwana; Constantin T Yiannoutsos; Maya L Petersen; Jeffrey N Martin
Journal:  Curr HIV/AIDS Rep       Date:  2010-11       Impact factor: 5.071

5.  Retention in care and connection to care among HIV-infected patients on antiretroviral therapy in Africa: estimation via a sampling-based approach.

Authors:  Elvin H Geng; David V Glidden; Mwebesa Bosco Bwana; Nicolas Musinguzi; Nneka Emenyonu; Winnie Muyindike; Katerina A Christopoulos; Torsten B Neilands; Constantin T Yiannoutsos; Steven G Deeks; David R Bangsberg; Jeffrey N Martin
Journal:  PLoS One       Date:  2011-07-26       Impact factor: 3.240

Review 6.  Retention in HIV care between testing and treatment in sub-Saharan Africa: a systematic review.

Authors:  Sydney Rosen; Matthew P Fox
Journal:  PLoS Med       Date:  2011-07-19       Impact factor: 11.069

7.  Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America.

Authors:  Benjamin H Chi; Constantin T Yiannoutsos; Andrew O Westfall; Jamie E Newman; Jialun Zhou; Carina Cesar; Martin W G Brinkhof; Albert Mwango; Eric Balestre; Gabriela Carriquiry; Thira Sirisanthana; Henri Mukumbi; Jeffrey N Martin; Anna Grimsrud; Melanie Bacon; Rodolphe Thiebaut
Journal:  PLoS Med       Date:  2011-10-25       Impact factor: 11.069

8.  Are Expert Patients an Untapped Resource for ART Provision in Sub-Saharan Africa?

Authors:  Tom Decroo; Wim Van Damme; Guy Kegels; Daniel Remartinez; Freya Rasschaert
Journal:  AIDS Res Treat       Date:  2012-04-19

9.  Factors associated with loss to clinic among HIV patients not yet known to be eligible for antiretroviral therapy (ART) in Mozambique.

Authors:  Rituparna Pati; Maria Lahuerta; Batya Elul; Mie Okamura; Maria Fernanda Alvim; Bruce Schackman; Heejung Bang; Rufino Fernandes; Americo Assan; Josue Lima; Denis Nash
Journal:  J Int AIDS Soc       Date:  2013-06-10       Impact factor: 5.396

10.  The journey to antiretroviral therapy in Karnataka, India: who was lost on the road?

Authors:  Suresh Shastri; Srinath Sathyanarayna; Sharath Burugina Nagaraja; Ajay Mv Kumar; Bharat Rewari; Anthony D Harries; Rony Zachariah
Journal:  J Int AIDS Soc       Date:  2013-08-27       Impact factor: 5.396

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  5 in total

1.  Moving past the 'pre-treatment' era of HIV care.

Authors:  Mark J Siedner
Journal:  Public Health Action       Date:  2014-12-21

2.  Correlates of Late Presentation to HIV care in a South Indian Cohort.

Authors:  Satish Rao; Satheesh Av; Bhaskaran Unnikrishnan; Deepak Madi; Avinash K Shetty
Journal:  Am J Trop Med Hyg       Date:  2018-11       Impact factor: 2.345

3.  The Convergence of Disclosure Concerns and Poverty Contributes to Loss to HIV Care in India: A Qualitative Study.

Authors:  Jared Perlo; Isabella Colocci; Sai Shanthanand Rajagopal; Theresa S Betancourt; Amrose Pradeep; Kenneth H Mayer; Nagalingeswaran Kumarasamy; Conall O'Cleirigh; Brian T Chan
Journal:  J Int Assoc Provid AIDS Care       Date:  2020 Jan-Dec

4.  Why are HIV-infected people not started on antiretroviral therapy? A mixed-methods study from Gujarat, India.

Authors:  S Chawla; K Shringarpure; B Modi; R Sharma; B B Rewari; A N Shah; P B Verma; A R Dongre; A M V Kumar
Journal:  Public Health Action       Date:  2017-09-21

5.  Alarming attrition rates among HIV-infected individuals in pre-antiretroviral therapy care in Myanmar, 2011-2014.

Authors:  Myo Minn Oo; Vivek Gupta; Thet Ko Aung; Nang Thu Thu Kyaw; Htun Nyunt Oo; Ajay Mv Kumar
Journal:  Glob Health Action       Date:  2016-08-24       Impact factor: 2.640

  5 in total

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