Literature DB >> 26398143

Liquisolid technology: What it can do for NSAIDs delivery?

Leila Azharshekoufeh B1, Javad Shokri2, Khosro Adibkia3, Yousef Javadzadeh4.   

Abstract

Liquisolid technology is also known as powder solution technology and is the technique which deals with the solubility term. This technology has been used to modify the dissolution rate of many drugs. Using this technique, many drugs exhibited enhanced or retarded dissolution rate. Non-steroidal anti-inflammatory drugs are among the highly important medications whose bioavailability is affected by the lower dissolution rate. In order to enhance the dissolution rate and subsequently the bioavailability of some of these drugs, liquisolid technology was used. This study reviewed the application of this useful technique for enhancing the dissolution rate of these important drugs and also the obtained results have been discussed in more details.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Bioavailability; Dissolution rate; Liquisolid; NSAIDs

Mesh:

Substances:

Year:  2015        PMID: 26398143     DOI: 10.1016/j.colsurfb.2015.09.014

Source DB:  PubMed          Journal:  Colloids Surf B Biointerfaces        ISSN: 0927-7765            Impact factor:   5.268


  3 in total

1.  Liquigroud technique: a new concept for enhancing dissolution rate of glibenclamide by combination of liquisolid and co-grinding technologies.

Authors:  Leila Azharshekoufeh; Javad Shokri; Mohammad Barzegar-Jalali; Yousef Javadzadeh
Journal:  Bioimpacts       Date:  2017-02-28

Review 2.  Recent advances in improving oral drug bioavailability by cocrystals.

Authors:  Shahram Emami; Mohammadreza Siahi-Shadbad; Khosro Adibkia; Mohammad Barzegar-Jalali
Journal:  Bioimpacts       Date:  2018-05-31

Review 3.  Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs.

Authors:  Xingwang Zhang; Huijie Xing; Yue Zhao; Zhiguo Ma
Journal:  Pharmaceutics       Date:  2018-06-23       Impact factor: 6.321

  3 in total

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