| Literature DB >> 26398143 |
Leila Azharshekoufeh B1, Javad Shokri2, Khosro Adibkia3, Yousef Javadzadeh4.
Abstract
Liquisolid technology is also known as powder solution technology and is the technique which deals with the solubility term. This technology has been used to modify the dissolution rate of many drugs. Using this technique, many drugs exhibited enhanced or retarded dissolution rate. Non-steroidal anti-inflammatory drugs are among the highly important medications whose bioavailability is affected by the lower dissolution rate. In order to enhance the dissolution rate and subsequently the bioavailability of some of these drugs, liquisolid technology was used. This study reviewed the application of this useful technique for enhancing the dissolution rate of these important drugs and also the obtained results have been discussed in more details.Entities:
Keywords: Bioavailability; Dissolution rate; Liquisolid; NSAIDs
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Year: 2015 PMID: 26398143 DOI: 10.1016/j.colsurfb.2015.09.014
Source DB: PubMed Journal: Colloids Surf B Biointerfaces ISSN: 0927-7765 Impact factor: 5.268