Literature DB >> 26397882

Exsanguinating bleeding following tooth extraction in a 12-year-old girl: a rare case of acquired haemophilia A.

Kimito Todo1, Tadaki Ohmae, Toshio Osamura, Nobuyuki Kiyosawa, Mitsuhiko Sugimoto, Midori Shima, Toshihiko Imamura, Shinsaku Imashuku.   

Abstract

Acquired haemophilia A (AHA) is a life-threatening haemorrhagic disorder that occurs with various underlying conditions such as autoimmune disease, drug reactions, lymphoproliferative diseases, solid tumours and pregnancy/postpartum status. However, in half of all reported cases, the underlying disease is unknown. Most AHA cases develop in adults; paediatric/adolescent cases are extremely rare. The main clinical symptom is bleeding into the skin, muscles, soft tissues and/or mucous membranes. Here, we report the case of an otherwise healthy 12-year-old girl who presented with prolonged bleeding postexodontia. After being diagnosed with AHA, she was successfully treated with recombinant activated factor VII infusion and oral prednisolone. To avoid such unanticipated bleeding when performing dental extraction, preoperative haemostatic screening tests are recommended.

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Year:  2015        PMID: 26397882     DOI: 10.1097/MBC.0000000000000355

Source DB:  PubMed          Journal:  Blood Coagul Fibrinolysis        ISSN: 0957-5235            Impact factor:   1.276


  1 in total

1.  A Case of a Patient Who Is Diagnosed with Mild Acquired Hemophilia A after Tooth Extraction Died of Acute Subdural Hematoma due to Head Injury.

Authors:  Tomohisa Kitamura; Tsuyoshi Sato; Eiji Ikami; Yosuke Fukushima; Tetsuya Yoda
Journal:  Case Rep Dent       Date:  2018-12-09
  1 in total

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