Literature DB >> 26396680

RORc Modulators for the Treatment of Autoimmune Diseases.

Ahmed F Abdel-Magid1.   

Abstract

Entities:  

Year:  2015        PMID： 26396680      PMCID： PMC4569874          DOI： 10.1021/acsmedchemlett.5b00313

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


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  2 in total

Review 1.  Modulators of the nuclear receptor retinoic acid receptor-related orphan receptor-γ (RORγ or RORc).

Authors:  Benjamin P Fauber; Steven Magnuson
Journal:  J Med Chem       Date:  2014-02-24       Impact factor: 7.446

Review 2.  The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis.

Authors:  Sandra M J Paulissen; Jan Piet van Hamburg; Wendy Dankers; Erik Lubberts
Journal:  Cytokine       Date:  2015-03-28       Impact factor: 3.861
  2 in total
  4 in total

1.  RORγt expression in Tregs promotes systemic lupus erythematosus via IL-17 secretion, alteration of Treg phenotype and suppression of Th2 responses.

Authors:  M A Kluger; A Nosko; T Ramcke; B Goerke; M C Meyer; C Wegscheid; M Luig; G Tiegs; R A K Stahl; O M Steinmetz
Journal:  Clin Exp Immunol       Date:  2017-01-05       Impact factor: 4.330

2.  Molecular dynamics simulations on RORγt: insights into its functional agonism and inverse agonism.

Authors:  Cong-Min Yuan; Hai-Hong Chen; Nan-Nan Sun; Xiao-Jun Ma; Jun Xu; Wei Fu
Journal:  Acta Pharmacol Sin       Date:  2019-07-17       Impact factor: 6.150

3.  Molecular Mechanism of Action of RORγt Agonists and Inverse Agonists: Insights from Molecular Dynamics Simulation.

Authors:  Nannan Sun; Congmin Yuan; Xiaojun Ma; Yonghui Wang; Xianfeng Gu; Wei Fu
Journal:  Molecules       Date:  2018-12-03       Impact factor: 4.411

4.  Microarray-based transcriptional profiling of a mouse model of autoimmune hepatitis.

Authors:  Yang Liu; Hao Chen; Jian-Heng Hao; Zhen-Cheng Li; Tiezheng Hou; Hui-Qin Hao
Journal:  FEBS Open Bio       Date:  2020-09-19       Impact factor: 2.792
  4 in total

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