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Literature DB >> 26396013

Effects of As2O3 on DNA methylation, genomic instability, and LTR retrotransposon polymorphism in Zea mays.

Filiz Aygun Erturk¹, Murat Aydin², Burcu Sigmaz³, M Sinan Taspinar⁴, Esra Arslan¹, Guleray Agar¹, Semra Yagci¹.

Abstract

Arsenic is a well-known toxic substance on the living organisms. However, limited efforts have been made to study its DNA methylation, genomic instability, and long terminal repeat (LTR) retrotransposon polymorphism causing properties in different crops. In the present study, effects of As2O3 (arsenic trioxide) on LTR retrotransposon polymorphism and DNA methylation as well as DNA damage in Zea mays seedlings were investigated. The results showed that all of arsenic doses caused a decreasing genomic template stability (GTS) and an increasing Random Amplified Polymorphic DNAs (RAPDs) profile changes (DNA damage). In addition, increasing DNA methylation and LTR retrotransposon polymorphism characterized a model to explain the epigenetically changes in the gene expression were also found. The results of this experiment have clearly shown that arsenic has epigenetic effect as well as its genotoxic effect. Especially, the increasing of polymorphism of some LTR retrotransposon under arsenic stress may be a part of the defense system against the stress.

Entities: Chemical Species

Keywords: As2O3; DNA methylation; Genomic instability; LTR retrotransposons polymorphism; Zea mays

Mesh：

Substances：

Year: 2015 PMID： 26396013 DOI： 10.1007/s11356-015-5426-2

Source DB: PubMed Journal: Environ Sci Pollut Res Int ISSN： 0944-1344 Impact factor: 4.223

38 in total

1. Effect of heavy metals on silencing of engineered long interspersed element-1 retrotransposon in nondividing neuroblastoma cell line.

Authors: Laleh Habibi; Mohammad Ali Shokrgozar; Mahdieh Motamedi; Seyed Mohammad Akrami
Journal: Iran Biomed J Date: 2013

2. Effects of Zinc, Copper and Iron Oxide Nanoparticles on Induced DNA Methylation, Genomic Instability and LTR Retrotransposon Polymorphism in Wheat (Triticum aestivum L.).

Authors: Kamil Haliloğlu; Aras Türkoğlu; Özge Balpınar; Hayrunnisa Nadaroğlu; Azize Alaylı; Peter Poczai
Journal: Plants (Basel) Date: 2022-08-24

2 in total

Effects of As2O3 on DNA methylation, genomic instability, and LTR retrotransposon polymorphism in Zea mays.

1. Effect of heavy metals on silencing of engineered long interspersed element-1 retrotransposon in nondividing neuroblastoma cell line.

2. Cytogenetic effects in human exposure to arsenic.

Review 3. Plant responses to abiotic stresses: heavy metal-induced oxidative stress and protection by mycorrhization.

4. MicroRNA responses to cellular stress.

Review 5. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation.

6. Arsenate-induced toxicity: effects on antioxidative enzymes and DNA damage in Vicia faba.

Review 7. Role of genomic instability in arsenic-induced carcinogenicity. A review.

8. Arsenate toxicity for wheat and lettuce in six Chinese soils with different properties.

9. Assessment of arsenic toxicity using Allium/Vicia root tip micronucleus assays.

10. Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor.

1. Changes of DNA methylation of Isoetes sinensis under Pb and Cd stress.

2. Effects of Zinc, Copper and Iron Oxide Nanoparticles on Induced DNA Methylation, Genomic Instability and LTR Retrotransposon Polymorphism in Wheat (Triticum aestivum L.).