BACKGROUND: Aortic knob width on chest radiography is independently related to cardiovascular disease. However, little is known about the correlation between aortic knob width and central hemodynamics. METHODS: Central blood pressure was measured invasively with diagnostic catheter in 92 patients with known or suspected coronary artery disease. RESULTS: Aortic knob width was positively associated with age (r = 0.42; p < 0.001), central systolic blood pressure (r = 0.35; p < 0.001) and central pulse pressure (r = 0.34; p < 0.001). Multivariate analysis showed that larger aortic knob width was independently related to the higher central systolic blood pressure. CONCLUSIONS: Lager aortic knob width on chest radiography is an independent predictor of increase of central systolic blood pressure.
BACKGROUND: Aortic knob width on chest radiography is independently related to cardiovascular disease. However, little is known about the correlation between aortic knob width and central hemodynamics. METHODS: Central blood pressure was measured invasively with diagnostic catheter in 92 patients with known or suspected coronary artery disease. RESULTS: Aortic knob width was positively associated with age (r = 0.42; p < 0.001), central systolic blood pressure (r = 0.35; p < 0.001) and central pulse pressure (r = 0.34; p < 0.001). Multivariate analysis showed that larger aortic knob width was independently related to the higher central systolic blood pressure. CONCLUSIONS: Lager aortic knob width on chest radiography is an independent predictor of increase of central systolic blood pressure.
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Keywords:
Aortic dilatation; arterial stiffness; central pulse pressure; central systolic pressure