Literature DB >> 26395516

Natural compounds with Wnt signal modulating activity.

Rolly G Fuentes1, Midori A Arai, Masami Ishibashi.   

Abstract

Covering: up to 2015 The Wnt signalling pathway is essential in many biological processes. The Wnt signal is associated with several diseases, particularly cancer and neurodegenerative diseases. Recently, high-throughput screening systems have been developed to rapidly identify compounds, including natural compounds, that target the Wnt signal. Some studies on natural modulators of the Wnt signal have also suggested their possible target. This review highlights some important natural compounds reported to regulate Wnt activity and describes their possible mechanism of action.

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Year:  2015        PMID： 26395516     DOI： 10.1039/c5np00074b

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  10 in total

1.  Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines.

Authors:  Lenisa Geron; Karina Bezerra Salomão; Kleiton Silva Borges; Augusto Faria Andrade; Carolina Alves Pereira Corrêa; Carlos Alberto Scrideli; Luiz Gonzaga Tone
Journal:  Cytotechnology       Date:  2018-10-29       Impact factor: 2.058

Review 2.  Screening study of cancer-related cellular signals from microbial natural products.

Authors:  Masami Ishibashi
Journal:  J Antibiot (Tokyo)       Date:  2021-06-30       Impact factor: 2.649

3.  Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells.

Authors:  Chandan Seth; Christophe Mas; Arwen Conod; Jens Mueller; Karsten Siems; Monika Kuciak; Isabel Borges; Ariel Ruiz I Altaba
Journal:  PLoS One       Date:  2016-12-14       Impact factor: 3.240

Review 4.  Wnt/β-Catenin Signaling in Oral Carcinogenesis.

Authors:  Montserrat Reyes; Tania Flores; Diego Betancur; Daniel Peña-Oyarzún; Vicente A Torres
Journal:  Int J Mol Sci       Date:  2020-06-30       Impact factor: 5.923

Review 5.  Screening for natural products that affect Wnt signaling activity.

Authors:  Masami Ishibashi
Journal:  J Nat Med       Date:  2019-05-30       Impact factor: 2.343

6.  Pharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4+ T cells.

Authors:  Jing Wen; Xin Li; Qing-Xia Zhao; Xiao-Fan Yang; Meng-Li Wu; Qihong Yan; Junbiao Chang; Haikun Wang; Xia Jin; Xiao Su; Kai Deng; Ling Chen; Jian-Hua Wang
Journal:  Emerg Microbes Infect       Date:  2022-12       Impact factor: 7.163

7.  Effects of Stress on Osteoblast Proliferation and Differentiation Based on Endoplasmic Reticulum Stress and Wntβ-Catenin Signaling Pathway.

Authors:  Hanming Zhong; Xiaoyu Yang; Shitie Li; Xin Lei
Journal:  Contrast Media Mol Imaging       Date:  2022-09-19       Impact factor: 3.009

8.  Dishevelled1-3 contribute to multidrug resistance in colorectal cancer via activating Wnt/β-catenin signaling.

Authors:  Kun Zhang; Minhui Li; Houyi Huang; Linpeng Li; Jie Yang; Li Feng; Junjie Gou; Mengju Jiang; Liaotian Peng; Linyi Chen; Ting Li; Ping Yang; Yuhan Yang; Yuanyuan Wang; Quekun Peng; Xiaozhen Dai; Tao Zhang
Journal:  Oncotarget       Date:  2017-12-14

9.  WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations.

Authors:  Gennaro Riccio; Maria Maisto; Sara Bottone; Nadia Badolati; Giovanni Battista Rossi; Gian Carlo Tenore; Mariano Stornaiuolo; Ettore Novellino
Journal:  Nutrients       Date:  2017-11-18       Impact factor: 5.717

Review 10.  Molecular and Cellular Pathogenesis of Endometriosis.

Authors:  Petra A B Klemmt; Anna Starzinski-Powitz
Journal:  Curr Womens Health Rev       Date:  2018-06
  10 in total

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