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Literature DB >> 26395141

Human pancreas development.

Rachel E Jennings¹, Andrew A Berry², James P Strutt², David T Gerrard³, Neil A Hanley¹.

Abstract

A wealth of data and comprehensive reviews exist on pancreas development in mammals, primarily mice, and other vertebrates. By contrast, human pancreatic development has been less comprehensively reviewed. Here, we draw together those studies conducted directly in human embryonic and fetal tissue to provide an overview of what is known about human pancreatic development. We discuss the relevance of this work to manufacturing insulin-secreting β-cells from pluripotent stem cells and to different aspects of diabetes, especially permanent neonatal diabetes, and its underlying causes.

Entities: Chemical

Keywords: Development; Embryo; Endoderm; Fetal; Foregut; Gestation; Human; Liver; Pancreas; Stem cells; Transcription factor; β-cells

Mesh：

Year: 2015 PMID： 26395141 DOI： 10.1242/dev.120063

Source DB: PubMed Journal: Development ISSN： 0950-1991 Impact factor: 6.868

Keyword Cloud
Cited

93 in total

1. Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.

Authors: Jing Liu; Amrita Banerjee; Charles A Herring; Jonathan Attalla; Ruiying Hu; Yanwen Xu; Qiujia Shao; Alan J Simmons; Prasanna K Dadi; Sui Wang; David A Jacobson; Bindong Liu; Emily Hodges; Ken S Lau; Guoqiang Gu
Journal: Dev Cell Date: 2019-01-07 Impact factor: 12.270

2. Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling.

Authors: Cyrille Ramond; Belin Selcen Beydag-Tasöz; Ajuna Azad; Martijn van de Bunt; Maja Borup Kjær Petersen; Nicola L Beer; Nicolas Glaser; Claire Berthault; Anna L Gloyn; Mattias Hansson; Mark I McCarthy; Christian Honoré; Anne Grapin-Botton; Raphael Scharfmann
Journal: Development Date: 2018-08-15 Impact factor: 6.868

Review 3. The impact of IUGR on pancreatic islet development and β-cell function.

Authors: Brit H Boehmer; Sean W Limesand; Paul J Rozance
Journal: J Endocrinol Date: 2017-08-14 Impact factor: 4.286

4. Metformin, beta-cell development, and novel processes following beta-cell ablation in zebrafish.

Authors: Georgia Wyett; Yann Gibert; Megan Ellis; Hozana A Castillo; Kathryn Aston-Mourney
Journal: Endocrine Date: 2017-12-22 Impact factor: 3.633

Review 5. The supply chain of human pancreatic β cell lines.

Authors: Raphael Scharfmann; Willem Staels; Olivier Albagli
Journal: J Clin Invest Date: 2019-09-03 Impact factor: 14.808

Review 6. Pancreas Volume and Fat Deposition in Diabetes and Normal Physiology: Consideration of the Interplay Between Endocrine and Exocrine Pancreas.

Authors: Yoshifumi Saisho
Journal: Rev Diabet Stud Date: 2016-08-10

Human pancreas development.

1. Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.

2. Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling.

Review 3. The impact of IUGR on pancreatic islet development and β-cell function.

4. Metformin, beta-cell development, and novel processes following beta-cell ablation in zebrafish.

Review 5. The supply chain of human pancreatic β cell lines.

Review 6. Pancreas Volume and Fat Deposition in Diabetes and Normal Physiology: Consideration of the Interplay Between Endocrine and Exocrine Pancreas.

Review 7. Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas.

Review 8. How, When, and Where Do Human β-Cells Regenerate?

Review 9. (Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives.

Review 10. Modelling the endocrine pancreas in health and disease.