Literature DB >> 26395039

Microfluidic multiplexed partitioning enables flexible and effective utilization of magnetic sensor arrays.

Daniel J B Bechstein1, Elaine Ng2, Jung-Rok Lee1, Stephanie G Cone3, Richard S Gaster4, Sebastian J Osterfeld5, Drew A Hall6, James A Weaver7, Robert J Wilson8, Shan X Wang9.   

Abstract

We demonstrate microfluidic partitioning of a giant magnetoresistive sensor array into individually addressable compartments that enhances its effective use. Using different samples and reagents in each compartment enables measuring of cross-reactive species and wide dynamic ranges on a single chip. This compartmentalization technique motivates the employment of high density sensor arrays for highly parallelized measurements in lab-on-a-chip devices.

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Year:  2015        PMID: 26395039     DOI: 10.1039/c5lc00953g

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  5 in total

Review 1.  Giant Magnetoresistance Biosensors in Biomedical Applications.

Authors:  Kai Wu; Denis Tonini; Shuang Liang; Renata Saha; Vinit Kumar Chugh; Jian-Ping Wang
Journal:  ACS Appl Mater Interfaces       Date:  2022-02-15       Impact factor: 10.383

2.  Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus.

Authors:  Jung-Rok Lee; D James Haddon; Hannah E Wand; Jordan V Price; Vivian K Diep; Drew A Hall; Michelle Petri; Emily C Baechler; Imelda M Balboni; Paul J Utz; Shan X Wang
Journal:  Sci Rep       Date:  2016-06-09       Impact factor: 4.379

3.  Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors.

Authors:  Jung-Rok Lee; Iris Appelmann; Cornelius Miething; Tyler O Shultz; Daniel Ruderman; Dokyoon Kim; Parag Mallick; Scott W Lowe; Shan X Wang
Journal:  Theranostics       Date:  2018-02-03       Impact factor: 11.556

4.  Design of micromagnetic arrays for on-chip separation of superparamagnetic bead aggregates and detection of a model protein and double-stranded DNA analytes.

Authors:  Stefano Rampini; Peng Li; Dhruv Gandhi; Marina Mutas; Ying Fen Ran; Michael Carr; Gil U Lee
Journal:  Sci Rep       Date:  2021-03-05       Impact factor: 4.379

5.  Magneto-nanosensor platform for probing low-affinity protein-protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction.

Authors:  Jung-Rok Lee; Daniel J B Bechstein; Chin Chun Ooi; Ashka Patel; Richard S Gaster; Elaine Ng; Lino C Gonzalez; Shan X Wang
Journal:  Nat Commun       Date:  2016-07-22       Impact factor: 14.919

  5 in total

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