Literature DB >> 26394180

Early and Long-term Outcomes of Older Adults after Acute Care Encounters for Chronic Obstructive Pulmonary Disease Exacerbation.

Liza Genao1,2, Michael T Durheim1,3, Xiaojuan Mi3, Jamie L Todd1,3, Heather E Whitson1,4,5,2, Lesley H Curtis1,3.   

Abstract

RATIONALE: Older patients are at high risk of death and rehospitalization after hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AE-COPD). Emergency department visits comprise a substantial portion of acute care encounters in this patient population. The risks of mortality and repeat acute care encounters, including both hospital readmission and repeat emergency department visits, after AE-COPD among older adults are not well understood.
OBJECTIVES: To examine early and long-term rates of death and repeat acute care encounters after hospitalization or emergency department visit for AE-COPD in Medicare fee-for-service beneficiaries and to identify patient characteristics, including medical comorbid conditions, associated with these outcomes.
METHODS: A retrospective analysis was conducted using a nationally representative 5% sample of Medicare fee-for-service claims data from the U.S. Centers for Medicare and Medicaid Services to identify Medicare beneficiaries 65 years or older who had an acute care episode for an AE-COPD between January 1, 2006, and December 31, 2010 (n = 52,741). Outcomes of interest were all-cause mortality, repeat acute care encounters for any cause, and repeat acute care encounters for AE-COPD at 30 days, 1 year, and 3 years.
MEASUREMENTS AND MAIN RESULTS: Acute care encounters, including hospitalizations and emergency department visits for AE-COPD, were associated with substantial subsequent mortality risk, with 4.6, 24.4, and 48.2% dying by 30 days, 1 year, and 3 years, respectively. The risk of repeat hospitalization or emergency department visit was similarly high, with 1 in 4 patients having a repeat acute care encounter within 30 days of discharge, increasing to 9 in 10 in the next 3 years. Several comorbid conditions and other patient factors, including heart failure, malnutrition, dual eligibility for Medicare and Medicaid, and prior supplemental oxygen use, were independently associated with increased risk of repeat acute care encounter.
CONCLUSIONS: Repeat hospitalizations and emergency department visits and death are common in older fee-for-service Medicare beneficiaries seen in acute care for AE-COPD. Our results suggest that addressing important comorbid conditions, such as heart failure or malnutrition, and targeting resources to oxygen-dependent or dual Medicare- and Medicaid-eligible patients may help modify these outcomes.

Entities:  

Keywords:  Medicare; chronic obstructive pulmonary disease; health outcomes

Mesh:

Year:  2015        PMID: 26394180      PMCID: PMC4722826          DOI: 10.1513/AnnalsATS.201504-250OC

Source DB:  PubMed          Journal:  Ann Am Thorac Soc        ISSN: 2325-6621


  31 in total

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2.  Accuracy of ICD-9-CM codes for identifying cardiovascular and stroke risk factors.

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Journal:  Ann Am Thorac Soc       Date:  2014-06

Review 4.  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

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Journal:  Am J Respir Crit Care Med       Date:  2012-08-09       Impact factor: 21.405

5.  Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort.

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Journal:  Respir Med       Date:  2013-06-19       Impact factor: 3.415

6.  Understanding why patients with COPD get readmitted: a large national study to delineate the Medicare population for the readmissions penalty expansion.

Authors:  Tina Shah; Matthew M Churpek; Marcelo Coca Perraillon; R Tamara Konetzka
Journal:  Chest       Date:  2015-05       Impact factor: 9.410

7.  Comparative ability of comorbidity classification methods for administrative data to predict outcomes in patients with chronic obstructive pulmonary disease.

Authors:  Peter C Austin; Matthew B Stanbrook; Geoffrey M Anderson; Alice Newman; Andrea S Gershon
Journal:  Ann Epidemiol       Date:  2012-10-31       Impact factor: 3.797

8.  Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD.

Authors:  Karin H Groenewegen; Annemie M W J Schols; Emiel F M Wouters
Journal:  Chest       Date:  2003-08       Impact factor: 9.410

9.  The coexistence of asthma and chronic obstructive pulmonary disease (COPD): prevalence and risk factors in young, middle-aged and elderly people from the general population.

Authors:  Roberto de Marco; Giancarlo Pesce; Alessandro Marcon; Simone Accordini; Leonardo Antonicelli; Massimiliano Bugiani; Lucio Casali; Marcello Ferrari; Gabriele Nicolini; Maria Grazia Panico; Pietro Pirina; Maria Elisabetta Zanolin; Isa Cerveri; Giuseppe Verlato
Journal:  PLoS One       Date:  2013-05-10       Impact factor: 3.240

Review 10.  Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality -- a systematic review.

Authors:  Milo A Puhan; Madlaina Scharplatz; Thierry Troosters; Johann Steurer
Journal:  Respir Res       Date:  2005-06-08
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  15 in total

Review 1.  Deterioration of Limb Muscle Function during Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Authors:  Raolat M Abdulai; Tina Jellesmark Jensen; Naimish R Patel; Michael I Polkey; Paul Jansson; Bartolomé R Celli; Stephen I Rennard
Journal:  Am J Respir Crit Care Med       Date:  2018-02-15       Impact factor: 21.405

2.  Investigating the impact of intervention refusal on hospital readmission.

Authors:  Alexis Coulourides Kogan; Eileen Koons; Susan Enguidanos
Journal:  Am J Manag Care       Date:  2017-12-01       Impact factor: 2.229

3.  Effect of early hospital readmission and comorbid conditions on subsequent long-term mortality after transient ischemic attack.

Authors:  Mohammed Yousufuddin; Nathan Young; Lawrence Keenan; Tammy Olson; Jessica Shultz; Taylor Doyle; Eimad Ahmmad; Kogulavadanan Arumaithurai; Paul Takahashi; Mohammad Hassan Murad
Journal:  Brain Behav       Date:  2017-11-22       Impact factor: 2.708

4.  Malnutrition, Airflow Limitation and Severe Emphysema are Risks for Exacerbation of Chronic Obstructive Pulmonary Disease in Japanese Subjects: A Retrospective Single-Center Study.

Authors:  Mutsuo Yamaya; Osamu Usami; Shoichi Nakayama; Naoki Tode; Aya Yamada; Shunsuke Ito; Fumiya Omata; Haruki Momma; Masakatsu Funakubo; Masakazu Ichinose
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-04-22

5.  Risk factors for new-onset atrial fibrillation in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Authors:  Qiangru Huang; Huaiyu Xiong; Tiankui Shuai; Meng Zhang; Chuchu Zhang; Yalei Wang; Lei Zhu; Jiaju Lu; Jian Liu
Journal:  PeerJ       Date:  2020-12-02       Impact factor: 2.984

6.  Identifying patterns of health care utilisation among physical elder abuse victims using Medicare data and legally adjudicated cases: protocol for case-control study using data linkage and machine learning.

Authors:  Tony Rosen; Yuhua Bao; Yiye Zhang; Sunday Clark; Katherine Wen; Alyssa Elman; Philip Jeng; Elizabeth Bloemen; Daniel Lindberg; Richard Krugman; Jacquelyn Campbell; Ronet Bachman; Terry Fulmer; Karl Pillemer; Mark Lachs
Journal:  BMJ Open       Date:  2021-02-05       Impact factor: 2.692

7.  Continuity of Care Assessment Within a Vertically Integrated Care Management Organization Before and After COPD-Related Exacerbations.

Authors:  Morgan Justice Fuoco; Richard A Mularski; Benjamin Wu; Chad Moretz; Mary Ann McBurnie; Richard H Stanford; Phillip Crawford; Daniel Gratie; Bianca Salas
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-10-07

8.  Examining 30-day COPD readmissions through the emergency department.

Authors:  Michael E Rezaee; Charlotte E Ward; Bonita Nuanez; Daniel A Rezaee; Jeffrey Ditkoff; Alexandra Halalau
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2017-12-27

9.  [Integral approach to the acute exacerbation of chronic obstructive pulmonary disease].

Authors:  J González Del Castillo; F J Candel; J de la Fuente; F Gordo; F J Martín-Sánchez; R Menéndez; A Mujal; J Barberán
Journal:  Rev Esp Quimioter       Date:  2018-10-04       Impact factor: 1.553

10.  Impacts of Comorbid Chronic Obstructive Pulmonary Disease and Congestive Heart Failure on Prognosis of Critically Ill Patients.

Authors:  Ying Dai; Shaoyun Qin; Huaqin Pan; Tianyu Chen; Dachen Bian
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-10-28
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