Literature DB >> 26393742

Arrays of resonant nanopillars for biochemical sensing.

Ana L Hernández, R Casquel, M Holgado, I Cornago, F J Sanza, B Santamaría, M Maigler, F Fernández, A Lavín, M F Laguna.   

Abstract

In this Letter, we demonstrate for the first time the experimental capability for the biochemical sensing of resonant nanopillars (RNPs) arrays. These arrays are fabricated over a glass substrate and are optically integrated from the backside of this substrate. The reflectivity profiles of the RNPs arrays are measured by infiltrating different ethanol fractions in water in order to evaluate the optical response for the different refractive indexes, which range from 1.330 to 1.342. A linear fit of the resonant modes shift is observed as a function of the bulk refractive index of the liquid infiltrated. For the type of transducer analyzed, a relative sensitivity of 10017  cm(-1)/Refractive Index Unit (RIU) is achieved, allowing us to reach a competitive Limit of Detection (LoD) in the order of 1×10(-5)  RIU.

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Year:  2015        PMID: 26393742     DOI: 10.1364/OL.40.002370

Source DB:  PubMed          Journal:  Opt Lett        ISSN: 0146-9592            Impact factor:   3.776


  2 in total

1.  Development towards Compact Nitrocellulose-Based Interferometric Biochips for Dry Eye MMP9 Label-Free In-Situ Diagnosis.

Authors:  Beatriz Santamaría; María F Laguna; David López-Romero; Ana L Hernandez; Francisco J Sanza; Álvaro Lavín; Rafael Casquel; María V Maigler; Rocío L Espinosa; Miguel Holgado
Journal:  Sensors (Basel)       Date:  2017-05-19       Impact factor: 3.576

Review 2.  Engineering vertically interrogated interferometric sensors for optical label-free biosensing.

Authors:  Rafael Casquel; Miguel Holgado; María F Laguna; Ana L Hernández; Beatriz Santamaría; Álvaro Lavín; Pedro Herreros
Journal:  Anal Bioanal Chem       Date:  2020-02-14       Impact factor: 4.142

  2 in total

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