Literature DB >> 26392971

Sputum smear examination and time to diagnosis in patients with smear-negative pulmonary tuberculosis in the Pacific.

K Viney1, K Bissell2, K Tabutoa3, T Kienene3, N N Linh4, K Briand5, A D Harries6.   

Abstract

SETTING: National tuberculosis programmes (NTPs) in Kiribati and the Marshall Islands, 2006-2010.
OBJECTIVE: To determine the proportion of all tuberculosis (TB) cases that were pulmonary smear-negative, and for these patients to determine how many sputum smears were examined and the time from sputum smear examination to registration.
DESIGN: A retrospective cross-sectional study involving a record review of national TB and laboratory registers.
RESULTS: Of 2420 TB cases identified, 709 (29%) were registered as smear-negative pulmonary TB. Of the 695 (98%) with information on smear examination, 222 (32%) had no smear recorded, 61 (9%) had one smear, 86 (12%) two smears and 326 (47%) three smears. Among the 473 patients who had at least one smear, 238 (50%) were registered before sputum examination, 131 (28%) within 1 week, 72 (15%) between 1 and 4 weeks, and 34 (7%) >4 weeks after sputum examination.
CONCLUSION: NTPs in Kiribati and the Marshall Islands are diagnosing 29% of all TB patients as smear-negative pulmonary TB. Many patients do not have smears done or are registered before undergoing smear examination. Corrective measures are needed.

Entities:  

Keywords:  Pacific; operational research; pulmonary tuberculosis; smear-negative

Year:  2012        PMID: 26392971      PMCID: PMC4463071          DOI: 10.5588/pha.12.0030

Source DB:  PubMed          Journal:  Public Health Action        ISSN: 2220-8372


  12 in total

1.  Time between sputum examination and treatment in patients with smear-negative pulmonary tuberculosis.

Authors:  F M Salaniponi; F Gausi; J H Kwanjana; A D Harries
Journal:  Int J Tuberc Lung Dis       Date:  2000-06       Impact factor: 2.373

2.  The epidemiology of tuberculosis in Pacific Island countries and territories: 2000-2007.

Authors:  Kerr Viney; Janet O'Connor; Axel Wiegandt
Journal:  Asia Pac J Public Health       Date:  2011-01       Impact factor: 1.399

3.  Risk factors for negative sputum acid-fast bacilli smears in pulmonary tuberculosis: results from Dakar, Senegal, a city with low HIV seroprevalence.

Authors:  B Samb; P S Sow; S Kony; M Maynart-Badiane; G Diouf; S Cissokho; D Bâ; M Sané; F Klotz; M A Faye-Niang; S Mboup; I Ndoye; E Delaporte; A A Hane; A Samb; J P Coulaud; A M Coll-Seck; B Larouzé; J F Murray
Journal:  Int J Tuberc Lung Dis       Date:  1999-04       Impact factor: 2.373

Review 4.  An approach to the problems of diagnosing and treating adult smear-negative pulmonary tuberculosis in high-HIV-prevalence settings in sub-Saharan Africa.

Authors:  A D Harries; D Maher; P Nunn
Journal:  Bull World Health Organ       Date:  1998       Impact factor: 9.408

5.  Pulmonary tuberculosis in patients with diabetes mellitus.

Authors:  F Bacakoğlu; O K Başoğlu; G Cok; A Sayiner; M Ateş
Journal:  Respiration       Date:  2001       Impact factor: 3.580

Review 6.  A review of the diagnosis and treatment of smear-negative pulmonary tuberculosis.

Authors:  R Colebunders; I Bastian
Journal:  Int J Tuberc Lung Dis       Date:  2000-02       Impact factor: 2.373

7.  Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli.

Authors:  M A Behr; S A Warren; H Salamon; P C Hopewell; A Ponce de Leon; C L Daley; P M Small
Journal:  Lancet       Date:  1999-02-06       Impact factor: 79.321

Review 8.  Clinical diagnosis of smear-negative pulmonary tuberculosis in low-income countries: the current evidence.

Authors:  Kamran Siddiqi; Marie-Laurence Lambert; John Walley
Journal:  Lancet Infect Dis       Date:  2003-05       Impact factor: 25.071

9.  Transmission of tuberculosis from smear negative patients: a molecular epidemiology study.

Authors:  E Hernández-Garduño; V Cook; D Kunimoto; R K Elwood; W A Black; J M FitzGerald
Journal:  Thorax       Date:  2004-04       Impact factor: 9.139

Review 10.  Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies.

Authors:  Christie Y Jeon; Megan B Murray
Journal:  PLoS Med       Date:  2008-07-15       Impact factor: 11.069

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  1 in total

1.  Overdiagnosis of and treatment initiation delay in smear-negative pulmonary tuberculosis patients.

Authors:  Mareli M Claassens
Journal:  Public Health Action       Date:  2012-12-21
  1 in total

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