Literature DB >> 26392660

Clinical mimicry by herpetic ulceration in a HIV positive teenager.

Abhishek Bhardwaj1, Bhagirath S Rathore1, Charu Sharma2, Garima Singh1.   

Abstract

The human immunodeficiency virus (HIV) is known to cause altered disease presentations. We present here, the case of a 14-year-old boy who came to us with a chronic, painful, nonhealing ulcer of 4 months duration over the dorsum of right hand. Before our observation, he was variably diagnosed and treated as atypical mycobacterial infection, deep fungal infection, squamous cell carcinoma, and pyoderma gangrenosum. On administration of systemic corticosteroids his condition worsened, after which he was tested for, and found to be HIV positive. He was put onto valacyclovir, responded slowly, with healing after 2 months of antiviral therapy. The case report highlights unusual presentation in an under-considered age group and a slow response to otherwise effective therapy.

Entities:  

Keywords:  Human immunodeficiency virus; herpes; nonhealing ulcer; pyoderma gangrenosum

Year:  2015        PMID: 26392660      PMCID: PMC4555905          DOI: 10.4103/0253-7184.156734

Source DB:  PubMed          Journal:  Indian J Sex Transm Dis AIDS        ISSN: 2589-0557


  4 in total

Review 1.  Skin ulcers misdiagnosed as pyoderma gangrenosum.

Authors:  Roger H Weenig; Mark D P Davis; Patrick R Dahl; W P Daniel Su
Journal:  N Engl J Med       Date:  2002-10-31       Impact factor: 91.245

Review 2.  Herpes simplex virus: the importance of asymptomatic shedding.

Authors:  D M Koelle; A Wald
Journal:  J Antimicrob Chemother       Date:  2000-04       Impact factor: 5.790

Review 3.  Management of acyclovir-resistant herpes simplex and varicella-zoster virus infections.

Authors:  H H Balfour; C Benson; J Braun; B Cassens; A Erice; A Friedman-Kien; T Klein; B Polsky; S Safrin
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1994-03

4.  Herpes misdiagnosed as pyoderma gangrenosum.

Authors:  L Sorna Kumar; C Shanmugasekar; C Lakshmi; C R Srinivas
Journal:  Indian J Sex Transm Dis AIDS       Date:  2009-07
  4 in total
  1 in total

1.  Onycho-mucocutaneous syndrome secondary to human immunodeficiency virus disease.

Authors:  B Madhuri; Spandana P Hegde; Manjunath M Shenoy
Journal:  Indian J Sex Transm Dis AIDS       Date:  2021-07-27
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.