Tatiana Toro-Ramos1,2, Rosely Sichieri3, Daniel J Hoffman1. 1. a Department of Nutritional Sciences , Rutgers, The State University of New Jersey , New Brunswick , NJ , USA . 2. b New York Obesity Nutrition Research Center, St. Luke's-Roosevelt Hospital Center/Columbia University , New York , NY , USA , and. 3. c Institute of Social Medicine, State University of Rio de Janeiro , Maracanã , Rio de Janeiro , Brazil.
Abstract
BACKGROUND: The relationship between maternal body composition and foetal development is unclear. AIM: To determine the relationship between maternal body composition [fat mass (FM) and fat-free mass (FFM)] and foetal growth and birth weight, independent of potential confounding factors. SUBJECTS AND METHODS: This study consisted of 92 women, normal and overweight/obese, recruited from the Instituto Fernandes Figueira in Rio de Janeiro, Brazil. Body composition (FM and FFM) was estimated using bioelectrical impedance. Foetal growth was assessed using serial ultrasound measurements at the second and third trimester and infant's weight and length were measured at birth. Multiple linear regression analyses were used to determine the association between maternal FM and FFM and birth weight adjusted for gestational age (BWt) and change in estimated foetal weight (ΔEFW), controlling for infant gender, maternal serum glucose, energy intake, parity, height and income. RESULTS: Maternal FM, but not FFM, was positively associated with BWt (p = 0.02) and borderline with ΔEFW (p = 0.05). FM expressed as a percentage of body weight (%FM) showed a significant positive association with BWt (p < 0.001) and ΔEFW (p < 0.01). Using backward linear regression analysis, FM was a significant predictor of BWt (p < 0.001) and ΔEFW (p = 0.03), but not change in femur length. CONCLUSION: In this small sample of normal and overweight/obese women, maternal FM at mid-pregnancy is associated with neonatal BW and foetal growth.
BACKGROUND: The relationship between maternal body composition and foetal development is unclear. AIM: To determine the relationship between maternal body composition [fat mass (FM) and fat-free mass (FFM)] and foetal growth and birth weight, independent of potential confounding factors. SUBJECTS AND METHODS: This study consisted of 92 women, normal and overweight/obese, recruited from the Instituto Fernandes Figueira in Rio de Janeiro, Brazil. Body composition (FM and FFM) was estimated using bioelectrical impedance. Foetal growth was assessed using serial ultrasound measurements at the second and third trimester and infant's weight and length were measured at birth. Multiple linear regression analyses were used to determine the association between maternal FM and FFM and birth weight adjusted for gestational age (BWt) and change in estimated foetal weight (ΔEFW), controlling for infant gender, maternal serum glucose, energy intake, parity, height and income. RESULTS: Maternal FM, but not FFM, was positively associated with BWt (p = 0.02) and borderline with ΔEFW (p = 0.05). FM expressed as a percentage of body weight (%FM) showed a significant positive association with BWt (p < 0.001) and ΔEFW (p < 0.01). Using backward linear regression analysis, FM was a significant predictor of BWt (p < 0.001) and ΔEFW (p = 0.03), but not change in femur length. CONCLUSION: In this small sample of normal and overweight/obesewomen, maternal FM at mid-pregnancy is associated with neonatal BW and foetal growth.
Entities:
Keywords:
Birth weight; foetal growth; international; maternal body composition
Authors: Sarah J Pugh; Ana M Ortega-Villa; William Grobman; Stefanie N Hinkle; Roger B Newman; Mary Hediger; Jagteshwar Grewal; Deborah A Wing; Paul S Albert; Katherine L Grantz Journal: Public Health Nutr Date: 2019-02-11 Impact factor: 4.022
Authors: Elizabeth M Widen; Irene Tsai; Shalean M Collins; Pauline Wekesa; Joy China; Natalie Krumdieck; Joshua D Miller; Sheri D Weiser; Maricianah Onono; Sera L Young Journal: Eur J Clin Nutr Date: 2018-09-05 Impact factor: 4.016
Authors: Romina Fakhraei; Kathryn Denize; Alexandre Simon; Ayni Sharif; Julia Zhu-Pawlowsky; Alysha L J Dingwall-Harvey; Brian Hutton; Misty Pratt; Becky Skidmore; Nadera Ahmadzai; Nicola Heslehurst; Louise Hayes; Angela C Flynn; Maria P Velez; Graeme Smith; Andrea Lanes; Natalie Rybak; Mark Walker; Laura Gaudet Journal: Int J Environ Res Public Health Date: 2022-02-12 Impact factor: 3.390