Literature DB >> 26390361

Targeting the Achilles' heel of adult living donor liver transplant: Corner-sparing sutures with mucosal eversion technique of biliary anastomosis.

Vivek Vij1, Kausar Makki1, Vishal Kumar Chorasiya1, Gaurav Sood1, Ashish Singhal1, Puneet Dargan1.   

Abstract

Biliary complications are regarded as the Achilles' heel of liver transplantation, especially for living donor liver transplantation (LDLT) due to smaller, multiple ducts and difficult ductal anatomy. Overall biliary complications reported in most series are between 10% and 30%. This study describes our modified technique of biliary anastomosis and its effects on incidence of biliary complications. This was a single-center retrospective study of 148 adult LDLT recipients between December 2011 and June 2014. Group 1 (n = 40) consisted of the first 40 patients for whom the standard technique of biliary anastomosis (minimal hilar dissection during donor duct division, high hilar division of the recipient bile duct, and preservation of the recipient duct periductal tissue) was used. Group 2 (n = 108) consisted of 108 patients for whom biliary anastomosis was done with the addition of corner-sparing sutures and mucosal eversion of the recipient duct to the standard technique. Primary outcome measures included biliary complications (biliary leaks and strictures). Biliary complications occurred in 7/40 patients in group 1 (17.5%) and in 4/108 patients in group 2 (3.7%). The technical factors mentioned above are aimed at preserving the blood supply of the donor and recipient ducts and hold the key for minimizing biliary complications in adult-to-adult LDLT.
© 2015 American Association for the Study of Liver Diseases.

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Year:  2016        PMID: 26390361     DOI: 10.1002/lt.24343

Source DB:  PubMed          Journal:  Liver Transpl        ISSN: 1527-6465            Impact factor:   5.799


  5 in total

Review 1.  Management issues in post living donor liver transplant biliary strictures.

Authors:  Manav Wadhawan; Ajay Kumar
Journal:  World J Hepatol       Date:  2016-04-08

Review 2.  Endoscopic management of biliary strictures after living donor liver transplantation.

Authors:  Takeshi Tsujino; Hiroyuki Isayama; Hirofumi Kogure; Tatsuya Sato; Yousuke Nakai; Kazuhiko Koike
Journal:  Clin J Gastroenterol       Date:  2017-06-09

3.  Role of the Intramural Vascular Network of the Extrahepatic Bile Duct for the Blood Circulation in the Recipient Extrahepatic Bile Duct Used for Duct-to-Duct-Biliary-Anastomosis in Living Donor Liver Transplantation.

Authors:  Naotaka Yamaguchi; Ryusei Matsuyama; Yutaro Kikuchi; Sho Sato; Yasuhiro Yabushita; Yu Sawada; Yuki Homma; Takafumi Kumamoto; Kazuhisa Takeda; Daisuke Morioka; Itaru Endo; Hiroshi Shimada
Journal:  Transpl Int       Date:  2022-05-03       Impact factor: 3.842

Review 4.  Liver Transplant Outcomes in India.

Authors:  Narendra S Choudhary; Prashant Bhangui; Arvinder S Soin
Journal:  Clin Liver Dis (Hoboken)       Date:  2022-01-24

5.  Salvage PTBD in post living donor liver transplant patients with biliary complications-a single centre retrospective study.

Authors:  Amar Mukund; Ashok Choudhury; Swati Das; Viniyendra Pamecha; Shiv Kumar Sarin
Journal:  Br J Radiol       Date:  2020-01-30       Impact factor: 3.039

  5 in total

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