Literature DB >> 26389015

Omental transplantation for neuroendocrinological disorders.

Hernando Rafael1.   

Abstract

Neurosurgical evidences show that the aging process is initiated between 25 to 30 years of age, in the arcuate nucleus of the hypothalamus. Likewise, experimental and neurosurgical findings indicate that the progressive ischemia in the arcuate nucleus and adjacent nuclei are responsibles at the onset of obesity and, type 2 diabetes mellitus in adults, and essential arterial hypertension (EAH). On the contrary, an omental transplantation on the optic chiasma, carotid bifurcation and anterior perforated space can provoke rejuvenation, gradual loss of body weight, decrease or normalization of hyperglycemia and normalization of EAH; all of them, due to revascularization of the hypothalamic nuclei. Besides, our surgical method have best advantages than the bariatric surgery, against obesity and type 2 diabetes mellitus.

Entities:  

Keywords:  Arcuate nucleus; ghrelin; leptin; obesity; omental transplantation; type 2 diabetes

Year:  2015        PMID: 26389015      PMCID: PMC4568769     

Source DB:  PubMed          Journal:  Am J Neurodegener Dis        ISSN: 2165-591X


  90 in total

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Authors:  Marie Schaeffer; Fanny Langlet; Chrystel Lafont; François Molino; David J Hodson; Thomas Roux; Laurent Lamarque; Pascal Verdié; Emmanuel Bourrier; Bénédicte Dehouck; Jean-Louis Banères; Jean Martinez; Pierre-François Méry; Jacky Marie; Eric Trinquet; Jean-Alain Fehrentz; Vincent Prévot; Patrice Mollard
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