| Literature DB >> 26389015 |
Abstract
Neurosurgical evidences show that the aging process is initiated between 25 to 30 years of age, in the arcuate nucleus of the hypothalamus. Likewise, experimental and neurosurgical findings indicate that the progressive ischemia in the arcuate nucleus and adjacent nuclei are responsibles at the onset of obesity and, type 2 diabetes mellitus in adults, and essential arterial hypertension (EAH). On the contrary, an omental transplantation on the optic chiasma, carotid bifurcation and anterior perforated space can provoke rejuvenation, gradual loss of body weight, decrease or normalization of hyperglycemia and normalization of EAH; all of them, due to revascularization of the hypothalamic nuclei. Besides, our surgical method have best advantages than the bariatric surgery, against obesity and type 2 diabetes mellitus.Entities:
Keywords: Arcuate nucleus; ghrelin; leptin; obesity; omental transplantation; type 2 diabetes
Year: 2015 PMID: 26389015 PMCID: PMC4568769
Source DB: PubMed Journal: Am J Neurodegener Dis ISSN: 2165-591X