| Literature DB >> 26388576 |
E A Gorbunov1,2, J Nicoll3, A A Myslivets4, E V Kachaeva4, S A Tarasov4.
Abstract
Addition of Subetta to insulin (10 nM) increased insulin-stimulated glucose uptake 43% (p<0.001). Moreover, glucose uptake stimulated by insulin (10 nM) in the presence of Subetta was similar to that stimulated by 300 nM insulin. These findings suggest that Subetta significantly enhanced insulin sensitivity of tissues through stimulation of glucose transport to myocytes mediated by glucose transporter 4.Entities:
Keywords: Subetta; glucose uptake; insulin receptor; release-activity
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Year: 2015 PMID： 26388576 DOI： 10.1007/s10517-015-2992-8
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804