Literature DB >> 26388357

Neoplasms of the salivary glands: analysis of 727 histopathological reports in a single institution.

Renato Fortes Bittar1, Homero Penha Ferraro1, Francyelle Tereza Moraes Gonçalves1, Majoy Gonçalves Couto da Cunha1, Eliana Rodrigues Biamino1.   

Abstract

INTRODUCTION: Salivary gland tumors comprise three to ten percent of all head and neck tumors. The parotid gland is affected most often (64-80%). Malignant tumors constitute a minority, occurring in 15-32% of cases. Pleomorphic adenoma is the most common benign tumor, while mucoepidermoid carcinoma is a malignant neoplasm characterized by the highest incidence.
OBJECTIVES: The objective of this study was to conduct a cross-sectional study of all salivary gland tumors diagnosed in a tertiary hospital in the period between 1995 and 2013.
METHODS: We reviewed all salivary gland histopathological reports completed at a single institution. Patient demographics and clinical data were analyzed. We used Pearson's chi-square test (χ2) to determine statistical significance for the variables.
RESULTS: Neoplastic lesions amounted to 271 cases (37,27%). Pleomorphic adenoma was the most frequent benign tumor, while mucoepidermoid carcinoma was the most commonly found malignant tumor. Parotid gland showed a clear, statistically significant (p=0.045) preponderance of benign tumors. Age was the only predictor of malignancy (OR 1.03).
CONCLUSION: The present study is in agreement with the current literature regarding the most frequent types of tumors, incidence according to a type of gland and gender.

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Year:  2015        PMID: 26388357     DOI: 10.5604/00306657.1163578

Source DB:  PubMed          Journal:  Otolaryngol Pol        ISSN: 0030-6657


  2 in total

1.  Apurinic/apyrimidinic endonuclease 1 (APE1) is overexpressed in malignant transformation of salivary gland pleomorphic adenoma.

Authors:  Leorik Pereira Silva; Thalita Santana; Bruno Tavares Sedassari; Suzana Machado de Sousa; Ana Paula Veras Sobral; Roseana de Almeida Freitas; Carlos Augusto Galvão Barboza; Lélia Batista de Souza
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-05-18       Impact factor: 2.503

Review 2.  Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review.

Authors:  John Lennon Silva Cunha; Juan Carlos Hernandez-Guerrero; Oslei Paes de Almeida; Ciro Dantas Soares; Adalberto Mosqueda-Taylor
Journal:  Head Neck Pathol       Date:  2020-10-12
  2 in total

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