Literature DB >> 26388274

Single center retrospective analysis of early vs. delayed treatment in acute calculous cholecystitis: application of a clinical pathway and an economic analysis.

Michele Pisano1, Marco Ceresoli1, Andrea Allegri1, Eugenia Belotti2, Federico Coccolini1, Renata Colombi2, Roberto Manfredi1, Francesco Margarito2, Cecilia Merli2, Giulia Montori1, Dario Piazzalunga1, Luca Ansaloni1.   

Abstract

BACKGROUND: Treatment option and timing for surgery in case of acute calculous cholecystitis (ACC) is still a matter of discussion. Tokyo Guidelines (TG13) offers some rules but they don't reflect entirely the information of Evidence Based Medicine (EBM). This study aimed to draw some consideration from our practice in the application of the guidelines and put forward the clinical, economic and organizational effect of it.
METHODS: The study is a single center retrospective study based on administrative database formed by gathering information from clinical registry. Data were collected between January 1st, 2008 and April 30th, 2013. A cutoff point was established on May 15th, 2010 when we moved from a single surgeon method to a shared EBM method to treat ACC. The economic aspect was developed considering health service reimburse and hospital costs.
RESULTS: Five hundred and two patients were selected, 203 patients before the organizational change (Group 0) and 299 after (Group 1). In Group 0, 24.63% of the patients were treated with early laparoscopic cholecystectomy (ELC) and 39.4% received surgery delayed in second admission (DLC). After the change, 57.5% of the patients were treated with ELC while 13% were treated with DLC. Median length of stay (LOS) was significantly lower after the change (9.5 vs. 7.3, p<0.0001), and no difference in terms of complication was noticed.
CONCLUSION: Application of evidence based medicine in clinical practice resulted in better results. Economically, the clinical change resulted in a proper use of resources with a positive gap between the costs and refund to the hospital.

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Year:  2015        PMID: 26388274     DOI: 10.5505/tjtes.2015.62679

Source DB:  PubMed          Journal:  Ulus Travma Acil Cerrahi Derg


  2 in total

1.  Mortality risk estimation in acute calculous cholecystitis: beyond the Tokyo Guidelines.

Authors:  Ana María González-Castillo; Juan Sancho-Insenser; Maite De Miguel-Palacio; Josep-Ricard Morera-Casaponsa; Estela Membrilla-Fernández; María-José Pons-Fragero; Miguel Pera-Román; Luis Grande-Posa
Journal:  World J Emerg Surg       Date:  2021-05-11       Impact factor: 5.469

2.  Early vs. Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis - Single Center Experience.

Authors:  Goran Janjic; Milan Simatovic; Velimir Skrbic; Reuf Karabeg; Dragan Radulj
Journal:  Med Arch       Date:  2020-02
  2 in total

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