Literature DB >> 26386965

Therapeutic effects of uterine artery embolisation (UAE) and methotrexate (MTX) conservative therapy used in treatment of cesarean scar pregnancy.

Hua Yang1, Shuying Li2, Zhe Ma2, Yanju Jia2.   

Abstract

PURPOSES: Cesarean scar pregnancy (CSP) is a rare and severe complication after cesarean section. The incidence of CSP has been increased significantly in recent years. In this retrospective case study of 131 CSP patients, the therapeutic effects and prognosis were compared between the two treatment groups: uterine artery embolization and systemic methotrexate injection conservative therapy. In addition, the necessary of subsequent dilation and curettage as a further treatment was also evaluated.
METHODS: The 131 CSP patients were assigned into two groups receiving uterine artery embolization (UAE) or MTX conservative therapy. Based on patients' myometrial thickness and reducing degree of β-hCG level, each of the two treatment group was further divided into two subgroups according to whether the patient received subsequent dilation and curettage as further treatment. The therapeutic effect of two treatment groups was compared.
RESULTS: The results indicated that both UAE and MTX conservative treatment achieved the expected therapeutic effect, and the recovery time in dilation and curettage subgroup was significantly shorter than that of the non-curettage subgroup. One hundred and thirty patients resumed normal menstrual cycles within 3-10 months after the treatment.
CONCLUSIONS: The individualized therapeutic regimen is an important factor to achieve the desired therapeutic effect based on the specific indications. Dilation and curettage could shorten the recovery time significantly.

Entities:  

Keywords:  Cesarean scar pregnancy; Methotrexate; Uterine arteries embolism

Mesh:

Substances:

Year:  2015        PMID: 26386965     DOI: 10.1007/s00404-015-3881-0

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  4 in total

1.  Caesarean scar pregnancy: descriptive paper of three different types of management on a series of clinical cases.

Authors:  Ferdinando Antonio Gulino; Elisa Pappalardo; Carla Ettore; Antonio Simone Laganà; Stella Capriglione; Giuseppe Ettore
Journal:  Prz Menopauzalny       Date:  2020-07-13

2.  New ultrasound grading system for cesarean scar pregnancy and its implications for management strategies: An observational cohort study.

Authors:  Shin-Yu Lin; Chia-Jung Hsieh; Yi-An Tu; Yi-Ping Li; Chien-Nan Lee; Wen-Wei Hsu; Jin-Chung Shih
Journal:  PLoS One       Date:  2018-08-09       Impact factor: 3.240

3.  The value of 3-dimensional color Doppler in predicting intraoperative hemorrhage for cesarean scar pregnancy.

Authors:  Jie Liu; Yiqing Chai; Yang Yu; Liping Liu
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.889

4.  Management of Caesarean scar pregnancy with or without methotrexate before curettage: human chorionic gonadotropin trends and patient outcomes.

Authors:  Sheng Wang; Rajluxmee Beejadhursing; Xiangyi Ma; Ya Li
Journal:  BMC Pregnancy Childbirth       Date:  2018-07-04       Impact factor: 3.007

  4 in total

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