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Literature DB >> 26386336

CBL-2201. Report on a new designer drug: Napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate.

A A Kondrasenko¹, E V Goncharov², K P Dugaev², A I Rubaylo³.

Abstract

The (1)H, (13)C and (15)N nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FT-IR) and gas chromatography coupled to mass spectrometry (GC-MS) identification of a synthetic cannabinoid compound has been conducted. It was shown that this compound cannot be reliably distinguished from the closely related quinolin-8-yl indole-3-carboxylic acid derivative by an automatic search in MS library. Structural difference of the studied compound and known illicit compounds has been determined using 1D and 2D NMR spectroscopy. Analytical data for the identification of this compound were provided.

Entities: Chemical Gene

Keywords: CBL-2201; Cannabinoids; Designer drugs; GC–MS; Indole-3-carboxylic acid; NMR

Mesh：

Substances：

Year: 2015 PMID： 26386336 DOI： 10.1016/j.forsciint.2015.08.023

Source DB: PubMed Journal: Forensic Sci Int ISSN： 0379-0738 Impact factor: 2.395

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Cited

4 in total

4. The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities.

Authors: Mitchell Longworth; Samuel D Banister; James B C Mack; Michelle Glass; Mark Connor; Michael Kassiou
Journal: Forensic Toxicol Date: 2016-04-27 Impact factor: 4.096

4 in total

CBL-2201. Report on a new designer drug: Napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate.

1. Δ⁹-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats.

2. In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201).

3. Cytotoxicity and Antioxidant Potential of Novel 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole Derivatives.

4. The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities.

CBL-2201. Report on a new designer drug: Napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate.

1. Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats.

2. In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201).

3. Cytotoxicity and Antioxidant Potential of Novel 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole Derivatives.

4. The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities.

1. Δ⁹-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats.