Literature DB >> 26384823

Compressive mechanical compatibility of anisotropic porous Ti6Al4V alloys in the range of physiological strain rate for cortical bone implant applications.

Fuping Li1, Jinshan Li1,2, Hongchao Kou3,4, Tingting Huang1, Lian Zhou1.   

Abstract

Porous titanium and its alloys are believed to be promising materials for bone implant applications, since they can reduce the "stress shielding" effect by tailoring porosity and improve fixation of implant through bone ingrowth. In the present work, porous Ti6Al4V alloys for biomedical application were fabricated by diffusion bonding of alloy meshes. Compressive mechanical behavior and compatibility in the range of physiological strain rate were studied under quasi-static and dynamic conditions. The results show that porous Ti6Al4V alloys possess anisotropic structure with elongated pores in the out-of-plane direction. For porous Ti6Al4V alloys with 60-70 % porosity, more than 40 % pores are in the range of 200-500 μm which is the optimum pore size suited for bone ingrowth. Quasi-static Young's modulus and yield stress of porous Ti6Al4V alloys with 30-70 % relative density are in the range of 6-40 GPa and 100-500 MPa, respectively. Quasi-static compressive properties can be quantitatively tailored by porosity to match those of cortical bone. Strain rate sensitivity of porous Ti6Al4V alloys is related to porosity. Porous Ti6Al4V alloys with porosity higher than 50 % show enhanced strain rate sensitivity, which is originated from that of base materials and micro-inertia effect. Porous Ti6Al4V alloys with 60-70 % porosity show superior compressive mechanical compatibility in the range of physiological strain rate for cortical bone implant applications.

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Year:  2015        PMID: 26384823     DOI: 10.1007/s10856-015-5565-5

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  20 in total

1.  Mechanical properties of open-pore titanium foam.

Authors:  Thomas Imwinkelried
Journal:  J Biomed Mater Res A       Date:  2007-06-15       Impact factor: 4.396

2.  β-Type Zr-Nb-Ti biomedical materials with high plasticity and low modulus for hard tissue replacements.

Authors:  Li Nie; Yongzhong Zhan; Tong Hu; Xiaoxian Chen; Chenghui Wang
Journal:  J Mech Behav Biomed Mater       Date:  2013-08-28

3.  Tensile testing of bone over a wide range of strain rates: effects of strain rate, microstructure and density.

Authors:  T M Wright; W C Hayes
Journal:  Med Biol Eng       Date:  1976-11

4.  Osteoinduction of porous Ti implants with a channel structure fabricated by selective laser melting.

Authors:  A Fukuda; M Takemoto; T Saito; S Fujibayashi; M Neo; Deepak K Pattanayak; T Matsushita; K Sasaki; N Nishida; T Kokubo; T Nakamura
Journal:  Acta Biomater       Date:  2011-02-02       Impact factor: 8.947

5.  Compression deformation behavior of Ti-6Al-4V alloy with cellular structures fabricated by electron beam melting.

Authors:  X Y Cheng; S J Li; L E Murr; Z B Zhang; Y L Hao; R Yang; F Medina; R B Wicker
Journal:  J Mech Behav Biomed Mater       Date:  2012-10-16

6.  Mechanical behavior of regular open-cell porous biomaterials made of diamond lattice unit cells.

Authors:  S M Ahmadi; G Campoli; S Amin Yavari; B Sajadi; R Wauthle; J Schrooten; H Weinans; A A Zadpoor
Journal:  J Mech Behav Biomed Mater       Date:  2014-02-08

7.  Compressive behaviour of child and adult cortical bone.

Authors:  Caroline Öhman; Massimiliano Baleani; Carla Pani; Fulvia Taddei; Marco Alberghini; Marco Viceconti; Marco Manfrini
Journal:  Bone       Date:  2011-07-06       Impact factor: 4.398

8.  The effect of strain rate on the mechanical properties of human cortical bone.

Authors:  Ulrich Hansen; Peter Zioupos; Rebecca Simpson; John D Currey; David Hynd
Journal:  J Biomech Eng       Date:  2008-02       Impact factor: 2.097

Review 9.  Biocompatibility of Ti-alloys for long-term implantation.

Authors:  Mohamed Abdel-Hady Gepreel; Mitsuo Niinomi
Journal:  J Mech Behav Biomed Mater       Date:  2012-12-06

10.  Titanium-Based Biomaterials for Preventing Stress Shielding between Implant Devices and Bone.

Authors:  M Niinomi; M Nakai
Journal:  Int J Biomater       Date:  2011-06-22
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  2 in total

1.  A novel device for treatment of osteonecrosis of femoral head: Feasibility and preliminary efficacy of animal study.

Authors:  Bo Li; Lingjia Yu; Zhenfei Huang; Yongxin Liang; Guangping Li; Yu Zhao
Journal:  J Orthop Translat       Date:  2021-10-21       Impact factor: 5.191

2.  Cell Viability Assay and Surface Morphology Analysis of Carbonated Hydroxyapatite/Honeycomb/Titanium Alloy Coatings for Bone Implant Applications.

Authors:  Mona Sari; Ika Dewi Ana; Yusril Yusuf
Journal:  Bioengineering (Basel)       Date:  2022-07-18
  2 in total

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