| Literature DB >> 26380861 |
Derk B Kuiper1, Jorien Seggers1, Pamela Schendelaar1, Maaike L Haadsma2, Tessa J Roseboom3, Maas J Heineman4, Mijna Hadders-Algra5.
Abstract
This study evaluated the prevalence of asthma and asthma medication use in 213 4-year-old singletons followed from birth onwards, including three groups of children born following: (i) controlled ovarian hyperstimulation IVF/intracytoplasmic sperm injection (ICSI); (ii) modified natural cycle IVF/ICSI; and (iii) natural conception in subfertile couples. The rate of asthma medication was higher in the ovarian hyperstimulation-IVF/ICSI than in the subfertile group (adjusted odds ratios [aOR]: 1.96 [1.00-3.84]). Time to pregnancy, a proxy for the severity of subfertility, was not associated with asthma and asthma medication. In conclusion, controlled ovarian hyperstimulation-IVF/ICSI is associated with the use of asthma medication in 4-year-old offspring of subfertile couples.Entities:
Keywords: assisted reproductive techniques; asthma; asthma medication; in-vitro fertilization; time to pregnancy
Mesh:
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Year: 2015 PMID: 26380861 DOI: 10.1016/j.rbmo.2015.08.002
Source DB: PubMed Journal: Reprod Biomed Online ISSN: 1472-6483 Impact factor: 3.828