Literature DB >> 26380060

Screening for hepatocellular carcinoma by Egyptian physicians.

Sahar M Hassany1, Ehab F Abdou Moustafa1, Mohamed El Taher1, Afaf Adel Abdeltwab1, Hubert E Blum1.   

Abstract

AIM: To assess the practice of Egyptian physicians in screening patients for hepatocellular carcinoma (HCC).
METHODS: The study included 154 physicians from all over Egypt caring for patients at risk for HCC. The study was based on a questionnaire with 20 items. Each questionnaire consisted of two parts: (1) personal information regarding the physician (name, age, specialty and type of health care setting); and (2) professional experience in the care of patients at risk for HCC development (screening, knowledge about the cause and natural course of liver diseases and HCC risk).
RESULTS: Sixty-eight percent of doctors with an MD degree, 48% of doctors with a master degree or a diploma and 40% of doctors with a Bachelor of Medicine, Bachelor of Surgery certificate considered the hepatitis C virus (HCV) genotype as risk factor for HCC development (P < 0.05). Ninety percent of physicians specialized in tropical medicine, internal medicine or gastroenterology and 67% of physicians in other specialties advise patients to undergo screening for HCV and hepatitis B virus infection as well as liver cirrhosis (P < 0.05). Eighty-six percent of doctors in University Hospitals and 69% of Ministry of Health (MOH) doctors consider HCV infection as the leading cause of HCC in Egypt (P < 0.05). Seventy-two percent of doctors with an MD degree, 55% of doctors with a master degree or a diploma, 56% of doctors with an MBBCH certificate, 74% of doctors in University Hospitals and 46% of MOH hospital doctors consider abdominal ultrasonography as the most important investigation in HCC screening (P < 0.05). Sixty-five percent of physicians in tropical medicine, internal medicine or gastroenterology and 37% of physicians in other specialties recommend as HCC screening interval of 3 mo (P < 0.05). Seventy-one percent of doctors with an MD degree, 50% of doctors with a master degree or diploma and 60% of doctors with an MBBCH certificate follow the same recommendation.
CONCLUSION: In Egypt, physicians specialized in tropical medicine, internal medicine or gastroenterology with an MD degree and working in a University Hospital are best informed about HCC.

Entities:  

Keywords:  Egyptian physicians; Hepatocellular carcinoma; Hepatocellular carcinoma diagnosis; Hepatocellular carcinoma knowledge; Hepatocellular carcinoma management; Screening

Year:  2015        PMID: 26380060      PMCID: PMC4569594          DOI: 10.4251/wjgo.v7.i9.161

Source DB:  PubMed          Journal:  World J Gastrointest Oncol


  27 in total

1.  Knowledge of hepatocellular carcinoma screening guidelines and clinical practices among gastroenterologists.

Authors:  Pratima Sharma; Sameer D Saini; Latoya B Kuhn; Joel H Rubenstein; Darrell S Pardi; Jorge A Marrero; Philip S Schoenfeld
Journal:  Dig Dis Sci       Date:  2010-10-27       Impact factor: 3.199

2.  Gender-based outcomes differences in unresectable hepatocellular carcinoma.

Authors:  Shama C Buch; Venkateswarlu Kondragunta; Robert A Branch; Brian I Carr
Journal:  Hepatol Int       Date:  2007-12-15       Impact factor: 6.047

Review 3.  Radiologic diagnosis of hepatocellular carcinoma.

Authors:  M S Peterson; R L Baron
Journal:  Clin Liver Dis       Date:  2001-02       Impact factor: 6.126

4.  Causes of death in patients with unresectable hepatocellular carcinoma.

Authors:  O F M Couto; I Dvorchik; B I Carr
Journal:  Dig Dis Sci       Date:  2007-04-10       Impact factor: 3.199

5.  Hepatocellular carcinoma in Egypt: a single center study over a decade.

Authors:  Abdel-Rahman el-Zayadi; Hanaa M Badran; Eman M F Barakat; Mohy el-Deen Attia; Sherine Shawky; Mostafa K Mohamed; Osaima Selim; Ahmed Saeid
Journal:  World J Gastroenterol       Date:  2005-09-07       Impact factor: 5.742

6.  Natural history of untreatable hepatocellular carcinoma: A retrospective cohort study.

Authors:  Giuseppe Cabibbo; Marcello Maida; Chiara Genco; Pietro Parisi; Marco Peralta; Michela Antonucci; Giuseppe Brancatelli; Calogero Cammà; Antonio Craxì; Vito Di Marco
Journal:  World J Hepatol       Date:  2012-09-27

7.  Hepatocellular carcinoma surveillance and appropriate treatment options improve survival for patients with liver cirrhosis.

Authors:  Yuan-Hung Kuo; Sheng-Nan Lu; Chao-Long Chen; Yu-Fan Cheng; Chih-Yun Lin; Chao-Hung Hung; Chien-Hung Chen; Chi-Sin Changchien; Hsuan-Chih Hsu; Tsung-Hui Hu; Chuan-Mo Lee; Jing-Houng Wang
Journal:  Eur J Cancer       Date:  2010-01-08       Impact factor: 9.162

Review 8.  Similarities and differences in hepatitis B and C virus induced hepatocarcinogenesis.

Authors:  Erzsébet Szabó; Csilla Páska; Pál Kaposi Novák; Zsuzsa Schaff; András Kiss
Journal:  Pathol Oncol Res       Date:  2004-03-18       Impact factor: 3.201

9.  Expression of hepatitis B virus X protein in transgenic mice.

Authors:  Jun Xiong; Yu-Cheng Yao; Xiao-Yuan Zi; Jian-Xiu Li; Xin-Min Wang; Xu-Ting Ye; Shu-Min Zhao; Yong-Bi Yan; Hong-Yu Yu; Yi-Ping Hu
Journal:  World J Gastroenterol       Date:  2003-01       Impact factor: 5.742

10.  Management of hepatocellular carcinoma: an update.

Authors:  Jordi Bruix; Morris Sherman
Journal:  Hepatology       Date:  2011-03       Impact factor: 17.425

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  1 in total

1.  Role of T-Helper 9 Cells in Chronic Hepatitis C-Infected Patients.

Authors:  Mohamed E Ali; Omnia El-Badawy; Noha A Afifi; Abeer Sharaf Eldin; Elham Ahmed Hassan; Hamada M Halby; Mohamed Ahmed El-Mokhtar
Journal:  Viruses       Date:  2018-06-24       Impact factor: 5.048

  1 in total

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