| Literature DB >> 26379905 |
Yidong Cheng1, Xiao Yang1, Xiaheng Deng1, Xiaolei Zhang1, Pengchao Li1, Jun Tao1, Chao Qin1, Jifu Wei2, Qiang Lu1.
Abstract
Bladder cancer (BC) is the most common urological malignancy. Early diagnosis of BC is crucial to improve patient outcomes. Currently, metabolomics is a potential technique that can be used to detect BC. We reviewed current publications and synthesised the findings on BC and metabolomics, i.e. metabolite upregulation and downregulation. Fourteen metabolites (lactic acid, leucine, valine, phenylalanine, glutamate, histidine, aspartic acid, tyrosine, serine, uracil, hypoxanthine, carnitine, pyruvic acid and citric acid) were identified as potential biomarkers for BC. In conclusion, this systematic review presents new opportunities for the diagnosis of BC.Entities:
Keywords: Bladder cancer; mass spectrometry; metabolomics; systematic review
Year: 2015 PMID: 26379905 PMCID: PMC4565288
Source DB: PubMed Journal: Int J Clin Exp Med ISSN: 1940-5901