Literature DB >> 26379880

Combination of propranolol and sclerotherapy for treatment of infantile parotid hemangiomas.

Xiaorong Ma1, Mengling Chang1, Tianxiang Ouyang1, Daili Xu2, Miao Xu1, Jingwen Ke1, Jun Lin1, Jun Liu1, Jie Yu1, Huiping Chen1.   

Abstract

We aimed to evaluate the efficacy of combination of propranolol and sclerotherapy in treating parotid hemangiomas. Twenty-six parotid hemangiomas patients were subjected to combined treatment from January 2009 and June 2014. The effects of the therapy modality were evaluated. Nineteen patients were females and 7 were males. The median age of treatment initiation was 4.96 months. Twelve lesions were located on the left side parotid glands, while thirteen lesions affected the right side. One infant had bilateral lesions. One to six (average 2.04) injections were performed and the mean period for propranolol was 8.94 months. All the patients got satisfied aesthetic outcomes. No complications of propranolol or sclerotherapy occurred during the whole medication period. The study demonstrated that combination of propranolol and sclerotherapy was an effective and safe method for infantile parotid hemangiomas. Larger-scale studies should be performed to further investigate the long-term efficacy and results of the present combined method for infantile parotid hemangiomas.

Entities:  

Keywords:  Parotid hemangiomas; complication; propranolol; sclerotherapy

Year:  2015        PMID: 26379880      PMCID: PMC4565263     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  14 in total

1.  Combination of oral corticosteroids and polidocanol sclerotherapy in the management of infantile hemangiomas.

Authors:  Chander Grover; Pooja Arora; Ashwini Kedar; Priyanka Pal; Brahmanand Lal
Journal:  Dermatol Surg       Date:  2010-10-11       Impact factor: 3.398

2.  Complicated giant hemangioma: excision using cardiopulmonary bypass and deep hypothermia.

Authors:  K E Little; S Cywes; M R Davies; J H Louw
Journal:  J Pediatr Surg       Date:  1976-08       Impact factor: 2.545

3.  An update on the treatment of hemangiomas in children with interferon alfa-2a.

Authors:  J H Greinwald; D K Burke; D J Bonthius; N M Bauman; R J Smith
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1999-01

4.  Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites.

Authors:  H H Zhou; R P Koshakji; D J Silberstein; G R Wilkinson; A J Wood
Journal:  N Engl J Med       Date:  1989-03-02       Impact factor: 91.245

5.  Propranolol enhanced adipogenesis instead of induction of apoptosis of hemangiomas stem cells.

Authors:  Xiaorong Ma; Tinghui Zhao; Tianxiang Ouyang; Shujia Xin; Yueting Ma; Mengling Chang
Journal:  Int J Clin Exp Pathol       Date:  2014-06-15

6.  Surgical therapy of parotid hemangiomas.

Authors:  C Esposito; A Zupi; L Califano
Journal:  Pediatr Surg Int       Date:  2001-07       Impact factor: 1.827

7.  The response of parotid hemangiomas to the use of systemic interferon alfa-2a or corticosteroids.

Authors:  F Blei; M Isakoff; G Deb
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1997-08

Review 8.  Cervicofacial vascular anomalies. I. Hemangiomas and other benign vascular tumors.

Authors:  Denise M Adams; Anne W Lucky
Journal:  Semin Pediatr Surg       Date:  2006-05       Impact factor: 2.754

9.  Management of parotid hemangioma in 100 children.

Authors:  Arin K Greene; Gary F Rogers; John B Mulliken
Journal:  Plast Reconstr Surg       Date:  2004-01       Impact factor: 4.730

Review 10.  Management of infantile parotid gland hemangiomas: a 40-year experience.

Authors:  Hani Sinno; Stephanie Thibaudeau; Ryan Coughlin; Sachin Chitte; Bruce Williams
Journal:  Plast Reconstr Surg       Date:  2010-01       Impact factor: 4.730

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  4 in total

1.  Management of Head and Neck Hemangiomas in Adults: Oral Propranolol Versus Oral Itraconazole in Conjugation with Injection Sodium Tetra Decyl Sulphate.

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Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2018-06-04

2.  Effect of 22 Novel Cytochrome P450 2D6 (CYP2D6) Variants Found in the Chinese Population on Hemangeol Metabolism In Vitro.

Authors:  Bingqing Liang; Yunyun Zhan; Xiangxin Huang; Ermin Gu; Dapeng Dai; Jianping Cai; Guoxin Hu
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2016-12       Impact factor: 2.441

3.  Early vascular embolization of large orbital and periorbital infantile capillary hemangiomas; A case report.

Authors:  Manal Hadrawi; Amer Alghamdi; Nourah Alageel; Ghufran Abudawood; Fawaz Alshareef; Mawahib Abuauf
Journal:  Am J Ophthalmol Case Rep       Date:  2022-02-10

4.  A Retrospective Study of Lip Hemangiomas: Curative Effect of Oral Propranolol Combined with Topical Sclerotherapy.

Authors:  Jiaqi Ling; Kun Yang; Ran Huo; Dongsheng Zhang
Journal:  Biomed Res Int       Date:  2022-07-25       Impact factor: 3.246

  4 in total

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