[Integration of pyrolized bone graft material in major bone defects].

In a clinical post-treatment evaluation during the past 3 years the wound healing of bone defects after substitution with a pyrolized xenogenic bone graft was observed in 90 patients. In most cases we found that wound healing was impaired and that the material did not show any osteointegration. As a result, inflammatory reactions of the bone with loss or demarcation of the bone graft occurred. Although some authors have reported a stimulation of osteogenesis after implantation of pyrolized bone graft, we cannot confirm their view.