Literature DB >> 26377494

Prevalence of chronic kidney disease and its association with cardio-metabolic risk factors in the adult Romanian population: the PREDATORR study.

Eugen Moţa1, Simona Georgiana Popa2, Maria Moţa3,4, Adina Mitrea5, Mircea Penescu6, Liliana Tuţă7, Cristian Serafinceanu8, Nicolae Hâncu9, Liliana Gârneaţă6, Constantin Verzan6, Radu Lichiardopol8, Cornelia Zetu8, Cristina Căpuşă6, Dan Vlăduţiu10, Cristian Guja8, Doina Catrinoiu11, Cornelia Bala9, Gabriela Roman9, Gabriela Radulian8, Romulus Timar12, Bogdan Mihai13.   

Abstract

PURPOSE: PREDATORR is the first national study analyzing the prevalence of chronic kidney disease and its prognosis and association with socio-demographic, cardio-metabolic and lifestyle risk factors in the adult Romanian population.
METHODS: Chronic kidney disease was defined according to the KDIGO 2012 criteria as an estimated glomerular filtration rate <60 mL/min/1.73 m(2) and/or urinary albumin-to-creatinine ratio ≥30 mg/g. The socio-demographic, lifestyle and anamnestic data were collected through interviewer-administered questionnaires. Physical examination and biochemical assays were also performed.
RESULTS: This cross-sectional study conducted between December 2012 and February 2014 in Romania included 2717 adults. The overall age- and sex-adjusted prevalence of chronic kidney disease was 6.74 % (95 %CI 5.60-7.88 %), of which 3.31 % (2.50-4.13 %) had only reduced kidney function (estimated glomerular filtration rate <60 mL/min/1.73 m(2)), 2.98 % (2.21-3.76 %) had only albuminuria, and 0.45 % (0.14-0.74 %) had both. The prevalence of chronic kidney disease increased with age and was similar in women and in men. Age, hyperuricemia, impaired glucose regulation (diabetes/prediabetes), hypertriglyceridemia and a family history of renal disease were independent risk factors for the presence of chronic kidney disease.
CONCLUSIONS: The PREDATORR study showed a high prevalence of chronic kidney disease in the adult Romanian population providing data on its prognosis and association with several cardio-metabolic risk factors.

Entities:  

Keywords:  Cardio-metabolic risk factors; Chronic kidney disease; Epidemiology; PREDATORR; Romania

Mesh:

Year:  2015        PMID: 26377494     DOI: 10.1007/s11255-015-1109-7

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  26 in total

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Review 6.  Uric acid and chronic kidney disease: which is chasing which?

Authors:  Richard J Johnson; Takahiko Nakagawa; Diana Jalal; Laura Gabriela Sánchez-Lozada; Duk-Hee Kang; Eberhard Ritz
Journal:  Nephrol Dial Transplant       Date:  2013-03-29       Impact factor: 5.992

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Authors:  Gregorio T Obrador; Brian J G Pereira; Annamaria T Kausz
Journal:  Semin Nephrol       Date:  2002-11       Impact factor: 5.299

Review 8.  Hypertension in moderate-to-severe nondiabetic CKD patients.

Authors:  Julian Segura; Luis M Ruilope
Journal:  Adv Chronic Kidney Dis       Date:  2011-01       Impact factor: 3.620

9.  A new equation to estimate glomerular filtration rate.

Authors:  Andrew S Levey; Lesley A Stevens; Christopher H Schmid; Yaping Lucy Zhang; Alejandro F Castro; Harold I Feldman; John W Kusek; Paul Eggers; Frederick Van Lente; Tom Greene; Josef Coresh
Journal:  Ann Intern Med       Date:  2009-05-05       Impact factor: 25.391

Review 10.  Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis.

Authors:  Tahir Kanji; Mandark Gandhi; Catherine M Clase; Robert Yang
Journal:  BMC Nephrol       Date:  2015-04-19       Impact factor: 2.388

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  5 in total

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2.  LONG-TERM IMPROVEMENT OF GLUCOSE HOMEOSTASIS AND BODY COMPOSITION IN PATIENTS UNDERGOING LAPAROSCOPIC SLEEVE GASTRECTOMY.

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Journal:  Acta Endocrinol (Buchar)       Date:  2018 Oct-Dec       Impact factor: 0.877

3.  Associations of smoking with cardiometabolic profile and renal function in a Romanian population-based sample from the PREDATORR cross-sectional study.

Authors:  Simona Georgiana Popa; Maria Moţa; Florin Dumitru Mihălţan; Adina Popa; Ioana Munteanu; Eugen Moţa; Cristian Serafinceanu; Cristian Guja; Nicolae Hâncu; Doina Catrinoiu; Radu Lichiardopol; Cornelia Bala; Bogdan Mihai; Gabriela Radulian; Gabriela Roman; Romulus Timar
Journal:  Eur J Gen Pract       Date:  2017-12       Impact factor: 1.904

4.  Metabolic Syndrome and Chronic Renal Disease.

Authors:  Vaia D Raikou; Sotiris Gavriil
Journal:  Diseases       Date:  2018-01-24

Review 5.  Establishing the presence or absence of chronic kidney disease: Uses and limitations of formulas estimating the glomerular filtration rate.

Authors:  Ahmed Alaini; Deepak Malhotra; Helbert Rondon-Berrios; Christos P Argyropoulos; Zeid J Khitan; Dominic S C Raj; Mark Rohrscheib; Joseph I Shapiro; Antonios H Tzamaloukas
Journal:  World J Methodol       Date:  2017-09-26
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