Literature DB >> 26377162

Omitting edema measurement: how much acute malnutrition are we missing?

Severine Frison1, Francesco Checchi2, Marko Kerac3.   

Abstract

BACKGROUND: Acute malnutrition is a major public health issue in low-income countries. It includes both wasting and edematous malnutrition, but the terms wasting and acute malnutrition are often used interchangeably. Little is known about the burden of edematous malnutrition, and few large-scale surveys measure it.
OBJECTIVE: Most acute malnutrition might be captured by the measurement of wasting alone, but this is unknown. This article aims to fill this gap.
DESIGN: This article presents a secondary data analysis of 852 nutrition cross-sectional survey data sets of children aged 6-59 mo. The data sets assembled included surveys from East, West, South, and Central Africa; the Caribbean; and Asia. The overlap between edematous malnutrition and wasting was assessed, and the impact of including/excluding edema on acute malnutrition prevalence estimates was evaluated.
RESULTS: The prevalence of edematous malnutrition varied from 0% to 32.9%, and children were more likely to have bilateral edema in Central and South Africa (OR: 4; 95% CI: 2.8, 5.6). A large proportion of children with edematous malnutrition were not wasted [62% and 66% based on midupper arm circumference (MUAC) and weight-for-height (WFH), respectively], and most were not severely wasted (83% and 86% based on MUAC and WFH, respectively). When wasting and global acute malnutrition prevalence estimates as well as severe wasting and severe acute malnutrition prevalence estimates overall were compared, the differences between estimates were small (median of 0.0% and mean of 0.3% based on WFH and MUAC for global estimates and slightly higher median of 0.1% and mean of 0.4% based on MUAC and WFH, respectively, for the severe forms), but the picture was different at the regional level.
CONCLUSIONS: The terms acute malnutrition and wasting should not be used interchangeably. The omission of the measurement of edema can have important repercussions, especially at the nutrition program level.
© 2015 American Society for Nutrition.

Entities:  

Keywords:  acute malnutrition; edematous malnutrition; kwashiorkor; mid-upper arm circumference; nutrition surveillance; wasting; weight-for-height

Mesh:

Year:  2015        PMID: 26377162     DOI: 10.3945/ajcn.115.108282

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  10 in total

Review 1.  Measuring growth and medium- and longer-term outcomes in malnourished children.

Authors:  Victor O Owino; Alexia J Murphy-Alford; Marko Kerac; Paluku Bahwere; Henrik Friis; James A Berkley; Alan A Jackson
Journal:  Matern Child Nutr       Date:  2019-02-27       Impact factor: 3.092

Review 2.  Tuberculosis in children with severe acute malnutrition.

Authors:  Bryan J Vonasek; Kendra K Radtke; Paula Vaz; W Chris Buck; Chishala Chabala; Eric D McCollum; Olivier Marcy; Elizabeth Fitzgerald; Alexander Kondwani; Anthony J Garcia-Prats
Journal:  Expert Rev Respir Med       Date:  2022-02-28       Impact factor: 4.300

Review 3.  Severe childhood malnutrition.

Authors:  Zulfiqar A Bhutta; James A Berkley; Robert H J Bandsma; Marko Kerac; Indi Trehan; André Briend
Journal:  Nat Rev Dis Primers       Date:  2017-09-21       Impact factor: 52.329

4.  Evaluation of the treatment guidelines, practices and outcomes of complicated severe acute malnutrition in children aged 0-59 months in sub-Saharan Africa: a study protocol for the SAMAC study.

Authors:  Janet Adede Carboo; Martani Lombard; Cornelia Conradie; Robin Claire Dolman; Cristian Ricci
Journal:  Pan Afr Med J       Date:  2020-08-04

5.  A novel, efficient method for estimating the prevalence of acute malnutrition in resource-constrained and crisis-affected settings: A simulation study.

Authors:  Severine Frison; Marko Kerac; Francesco Checchi; Jennifer Nicholas
Journal:  PLoS One       Date:  2017-11-01       Impact factor: 3.240

6.  Informing the management of acute malnutrition in infants aged under 6 months (MAMI): risk factor analysis using nationally-representative demographic & health survey secondary data.

Authors:  Marko Kerac; Severine Frison; Nichola Connell; Bethan Page; Marie McGrath
Journal:  PeerJ       Date:  2019-04-15       Impact factor: 2.984

7.  Edematous severe acute malnutrition is characterized by hypomethylation of DNA.

Authors:  Katharina V Schulze; Shanker Swaminathan; Sharon Howell; Aarti Jajoo; Natasha C Lie; Orgen Brown; Roa Sadat; Nancy Hall; Liang Zhao; Kwesi Marshall; Thaddaeus May; Marvin E Reid; Carolyn Taylor-Bryan; Xueqing Wang; John W Belmont; Yongtao Guan; Mark J Manary; Indi Trehan; Colin A McKenzie; Neil A Hanchard
Journal:  Nat Commun       Date:  2019-12-19       Impact factor: 14.919

8.  Child wasting before and after age two years: A cross-sectional study of 94 countries.

Authors:  Omar Karlsson; Rockli Kim; Saul Guerrero; Andreas Hasman; S V Subramanian
Journal:  EClinicalMedicine       Date:  2022-03-25

9.  Mid-Upper Arm Circumference (MUAC) shows strong geographical variations in children with edema: results from 2277 surveys in 55 countries.

Authors:  Jose Luis Alvarez; Nicky Dent; L Browne; Mark Myatt; André Briend
Journal:  Arch Public Health       Date:  2018-08-15

10.  'Severe malnutrition': thinking deeplyS, communicating simply.

Authors:  Marko Kerac; Marie McGrath; Nichola Connell; Chytanya Kompala; William H Moore; Jeanette Bailey; Robert Bandsma; James A Berkley; André Briend; Steve Collins; Tsinuel Girma; Jonathan C Wells
Journal:  BMJ Glob Health       Date:  2020-11
  10 in total

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