Literature DB >> 26376468

The complete genome sequence of a high pristinamycin-producing strain Streptomyces pristinaespiralis HCCB10218.

Jinzhong Tian1, Junjie Yang1, Lei Li1, Lijun Ruan2, Wei Wei2, Guosong Zheng1, Wei Zhao1, Jun Chen1, Weihong Jiang1, Mei Ge3, Yinhua Lu4.   

Abstract

Streptomyces pristinaespiralis produces the streptogramin-like antibiotic pristinamycin, which is a mixture of two structurally different components: pristinamycin I (PI) and pristinamycin II (PII). Herein, we report the complete genome sequence of a high pristinamycin-producing strain HCCB10218 (8.5 Mb) obtained by using PacBio RSII combined with Illumina HiSeq 2500 sequencing system. The genome sequence presented here provides clues for the mechanism underlying the higher pristinamycin production of HCCB10218.
Copyright © 2015 Elsevier B.V. All rights reserved.

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Keywords:  Genome sequence; Pristinamycin; Streptomyces pristinaespiralis

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Year:  2015        PMID: 26376468     DOI: 10.1016/j.jbiotec.2015.09.010

Source DB:  PubMed          Journal:  J Biotechnol        ISSN: 0168-1656            Impact factor:   3.307


  2 in total

1.  Complete genome sequence of high-yield strain S. lincolnensis B48 and identification of crucial mutations contributing to lincomycin overproduction.

Authors:  Ruida Wang; Fanjing Kong; Haizhen Wu; Bingbing Hou; Yajing Kang; Yuan Cao; Shiwei Duan; Jiang Ye; Huizhan Zhang
Journal:  Synth Syst Biotechnol       Date:  2020-04-13

Review 2.  Genome mining for drug discovery: progress at the front end.

Authors:  Richard H Baltz
Journal:  J Ind Microbiol Biotechnol       Date:  2021-12-23       Impact factor: 4.258

  2 in total

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