| Literature DB >> 26375584 |
Alexander Heifetz1, Mike J Bodkin1, Philip C Biggin2.
Abstract
In this issue, Nagase and colleagues report the discovery of the first selective nonpeptidic orexin 2 receptor (OX2R) agonists. The discovery of these OX2R selective agonists opens up new avenues for therapies related to the activation of the orexin system, especially with respect to the treatment of sleep disorders such as narcolepsy.Entities:
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Year: 2015 PMID： 26375584 DOI： 10.1021/acs.jmedchem.5b01394
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 8.039