Literature DB >> 26375309

Reprogramming aging through DOT1L inhibition.

Clara Soria-Valles1, Fernando G Osorio1, Carlos López-Otín1.   

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Year:  2015        PMID： 26375309      PMCID： PMC4825545          DOI： 10.1080/15384101.2015.1093443

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.

Authors:  Fernando G Osorio; Ignacio Varela; Ester Lara; Xose S Puente; Jesús Espada; Raffaella Santoro; José M P Freije; Mario F Fraga; Carlos López-Otín
Journal:  Aging Cell       Date:  2010-10-21       Impact factor: 9.304

2.  NF-κB activation impairs somatic cell reprogramming in ageing.

Authors:  Clara Soria-Valles; Fernando G Osorio; Ana Gutiérrez-Fernández; Alejandro De Los Angeles; Clara Bueno; Pablo Menéndez; José I Martín-Subero; George Q Daley; José M P Freije; Carlos López-Otín
Journal:  Nat Cell Biol       Date:  2015-07-27       Impact factor: 28.824

3.  Progressive methylation of ageing histones by Dot1 functions as a timer.

Authors:  Dirk De Vos; Floor Frederiks; Marit Terweij; Tibor van Welsem; Kitty F Verzijlbergen; Ekaterina Iachina; Erik L de Graaf; A F Maarten Altelaar; Gideon Oudgenoeg; Albert J R Heck; Jeroen Krijgsveld; Barbara M Bakker; Fred van Leeuwen
Journal:  EMBO Rep       Date:  2011-09-01       Impact factor: 8.807

4.  Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.

Authors:  Fernando G Osorio; Clea Bárcena; Clara Soria-Valles; Andrew J Ramsay; Félix de Carlos; Juan Cobo; Antonio Fueyo; José M P Freije; Carlos López-Otín
Journal:  Genes Dev       Date:  2012-09-26       Impact factor: 11.361

5.  Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome.

Authors:  Xose S Puente; Victor Quesada; Fernando G Osorio; Rubén Cabanillas; Juan Cadiñanos; Julia M Fraile; Gonzalo R Ordóñez; Diana A Puente; Ana Gutiérrez-Fernández; Miriam Fanjul-Fernández; Nicolas Lévy; José M P Freije; Carlos López-Otín
Journal:  Am J Hum Genet       Date:  2011-05-05       Impact factor: 11.025

Review 6.  The hallmarks of aging.

Authors:  Carlos López-Otín; Maria A Blasco; Linda Partridge; Manuel Serrano; Guido Kroemer
Journal:  Cell       Date:  2013-06-06       Impact factor: 41.582

7.  Chromatin-modifying enzymes as modulators of reprogramming.

Authors:  Tamer T Onder; Nergis Kara; Anne Cherry; Amit U Sinha; Nan Zhu; Kathrin M Bernt; Patrick Cahan; B Ogan Marcarci; Juli Unternaehrer; Piyush B Gupta; Eric S Lander; Scott A Armstrong; George Q Daley
Journal:  Nature       Date:  2012-03-04       Impact factor: 49.962
  7 in total
  5 in total

Review 1.  Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells.

Authors:  Dido Carrero; Clara Soria-Valles; Carlos López-Otín
Journal:  Dis Model Mech       Date:  2016-07-01       Impact factor: 5.758

2.  Senescence-Inflammatory Regulation of Reparative Cellular Reprogramming in Aging and Cancer.

Authors:  Javier A Menendez; Tomás Alarcón
Journal:  Front Cell Dev Biol       Date:  2017-05-05

Review 3.  DNA methylation aging clocks: challenges and recommendations.

Authors:  Christopher G Bell; Robert Lowe; Peter D Adams; Andrea A Baccarelli; Stephan Beck; Jordana T Bell; Brock C Christensen; Vadim N Gladyshev; Bastiaan T Heijmans; Steve Horvath; Trey Ideker; Jean-Pierre J Issa; Karl T Kelsey; Riccardo E Marioni; Wolf Reik; Caroline L Relton; Leonard C Schalkwyk; Andrew E Teschendorff; Wolfgang Wagner; Kang Zhang; Vardhman K Rakyan
Journal:  Genome Biol       Date:  2019-11-25       Impact factor: 13.583

Review 4.  The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes.

Authors:  Fiorella Sarubbo; Virve Cavallucci; Giovambattista Pani
Journal:  Cells       Date:  2022-01-23       Impact factor: 6.600

5.  Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein.

Authors:  Corentin Bon; Yang Si; Melanie Pernak; Magdalena Barbachowska; Eva Levi-Acobas; Veronique Cadet Daniel; Corinne Jallet; Dusan Ruzic; Nemanja Djokovic; Teodora Djikić; Katarina Nikolic; Ludovic Halby; Paola B Arimondo
Journal:  Molecules       Date:  2021-08-31       Impact factor: 4.411
  5 in total

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