Literature DB >> 26371384

T2MR and T2Candida: novel technology for the rapid diagnosis of candidemia and invasive candidiasis.

Michael A Pfaller1,2, Donna M Wolk3, Thomas J Lowery1.   

Abstract

Candidemia and other forms of invasive candidiasis pose a significant diagnostic challenge. In order to provide the best treatment, it is important to accurately detect the fungal infection and identify the species. Historically, diagnosis of Candida infections depended upon three classical laboratory approaches: microbiologic, immunologic, histopathologic; and now includes new methods such as radiographic techniques, molecular, proteomic and biochemical methods. The T2Candida Panel has introduced a new class of infectious disease diagnostics that can rapidly detect and identify the causative pathogen of sepsis directly from a patient blood sample in a culture-independent manner. This test enables detection of Candida directly from the patient sample, a significant advance for the rapid and accurate diagnosis of invasive candidiasis.

Entities:  

Keywords:  Candida; T2Candida; T2MR; blood stream infection; diagnosis; magnetic resonance; nanotechnology; sepsis

Mesh:

Year:  2015        PMID: 26371384     DOI: 10.2217/fmb.15.111

Source DB:  PubMed          Journal:  Future Microbiol        ISSN: 1746-0913            Impact factor:   3.165


  29 in total

1.  Evaluation of a Rapid Fungal Detection Panel for Identification of Candidemia at an Academic Medical Center.

Authors:  John P Bomkamp; Rand Sulaiman; Jennifer L Hartwell; Armisha Desai; Vera C Winn; Justin Wrin; Michelle L Kussin; Jon J Hiles
Journal:  J Clin Microbiol       Date:  2020-02-24       Impact factor: 5.948

Review 2.  Antifungal stewardship considerations for adults and pediatrics.

Authors:  Rana F Hamdy; Theoklis E Zaoutis; Susan K Seo
Journal:  Virulence       Date:  2016-09-02       Impact factor: 5.882

3.  A 72-h intervention for improvement of the rate of optimal antibiotic therapy in patients with bloodstream infections.

Authors:  R Murri; F Taccari; T Spanu; T D'Inzeo; I Mastrorosa; F Giovannenze; G Scoppettuolo; G Ventura; C Palazzolo; M Camici; S Lardo; B Fiori; M Sanguinetti; R Cauda; M Fantoni
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-10-19       Impact factor: 3.267

Review 4.  Syndromic Panel-Based Testing in Clinical Microbiology.

Authors:  Poornima Ramanan; Alexandra L Bryson; Matthew J Binnicker; Bobbi S Pritt; Robin Patel
Journal:  Clin Microbiol Rev       Date:  2017-11-15       Impact factor: 26.132

Review 5.  Diagnosing and Managing Sepsis by Probing the Host Response to Infection: Advances, Opportunities, and Challenges.

Authors:  Ian L Gunsolus; Timothy E Sweeney; Oliver Liesenfeld; Nathan A Ledeboer
Journal:  J Clin Microbiol       Date:  2019-06-25       Impact factor: 5.948

6.  T2 Magnetic Resonance Assay-Based Direct Detection of Three Lyme Disease-Related Borrelia Species in Whole-Blood Samples.

Authors:  Jessica L Snyder; Heidi Giese; Cheryl Bandoski-Gralinski; Jessica Townsend; Beck E Jacobson; Robert Shivers; Anna M Schotthoefer; Thomas R Fritsche; Clayton Green; Steven M Callister; John A Branda; Thomas J Lowery
Journal:  J Clin Microbiol       Date:  2017-05-31       Impact factor: 5.948

7.  Update on Non-Culture-Based Diagnostics for Invasive Fungal Disease.

Authors:  Gabriel Yan; Ka Lip Chew; Louis Yi Ann Chai
Journal:  Mycopathologia       Date:  2021-07-02       Impact factor: 2.574

Review 8.  Recent trends in molecular diagnostics of yeast infections: from PCR to NGS.

Authors:  Toni Gabaldón
Journal:  FEMS Microbiol Rev       Date:  2019-09-01       Impact factor: 16.408

Review 9.  New Microbiological Techniques for the Diagnosis of Bacterial Infections and Sepsis in ICU Including Point of Care.

Authors:  Anna Maria Peri; Adam Stewart; Anna Hume; Adam Irwin; Patrick N A Harris
Journal:  Curr Infect Dis Rep       Date:  2021-06-16       Impact factor: 3.725

Review 10.  Molecular Diagnosis of Yeast Infections.

Authors:  P Lewis White; Jessica S Price; Alan Cordey; Matthijs Backx
Journal:  Curr Fungal Infect Rep       Date:  2021-06-18
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