Literature DB >> 26370567

1H, 13C, 15N resonance assignments of the extracellular loop 1 domain (ECL1) of Streptococcus pneumoniae D39 FtsX, an essential cell division protein.

Yue Fu1, Kevin E Bruce2, Britta Rued2, Malcolm E Winkler2, David P Giedroc3.   

Abstract

FtsX is an integral membrane protein from Streptococcus pneumoniae (pneumococcus) that harbors an extracellular loop 1 domain (FtsX(Spn)ECL1) that interacts with PcsB, an peptidoglycan hydrolase that is essential for cell growth and division. Here, we report nearly complete backbone and side chain resonance assignments and a secondary structural analysis of FtsX(Spn)ECL1 (residues 47-168 of FtsX) as first steps toward structure determination of FtsX(Spn)ECL1.

Entities:  

Keywords:  ABC transporter; Allostery; Bacterial cell wall; Divisome; Extracellular signaling; Peptidoglycan hydrolysis

Mesh：

Substances：

Year:  2015        PMID： 26370567      PMCID： PMC4789122          DOI： 10.1007/s12104-015-9644-9

Source DB:  PubMed          Journal:  Biomol NMR Assign        ISSN： 1874-270X            Impact factor:   0.746


  7 in total

1.  Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXSpn cell division protein in Streptococcus pneumoniae D39.

Authors:  Lok-To Sham; Skye M Barendt; Kimberly E Kopecky; Malcolm E Winkler
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-17       Impact factor: 11.205

2.  Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.

Authors:  Daniela Mavrici; Mohlopheni J Marakalala; James M Holton; Daniil M Prigozhin; Christine L Gee; Yanjia J Zhang; Eric J Rubin; Tom Alber
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-19       Impact factor: 11.205

3.  Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae.

Authors:  Sergio G Bartual; Daniel Straume; Gro Anita Stamsås; Inés G Muñoz; Carlos Alfonso; Martín Martínez-Ripoll; Leiv Sigve Håvarstein; Juan A Hermoso
Journal:  Nat Commun       Date:  2014-05-08       Impact factor: 14.919

4.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

5.  Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors.

Authors:  P Sheffield; S Garrard; Z Derewenda
Journal:  Protein Expr Purif       Date:  1999-02       Impact factor: 1.650

6.  TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts.

Authors:  Yang Shen; Frank Delaglio; Gabriel Cornilescu; Ad Bax
Journal:  J Biomol NMR       Date:  2009-06-23       Impact factor: 2.835

7.  Involvement of FtsE ATPase and FtsX extracellular loops 1 and 2 in FtsEX-PcsB complex function in cell division of Streptococcus pneumoniae D39.

Authors:  Lok-To Sham; Katelyn R Jensen; Kevin E Bruce; Malcolm E Winkler
Journal:  MBio       Date:  2013-07-16       Impact factor: 7.867
  7 in total
  2 in total

1.  Biochemical characterization of essential cell division proteins FtsX and FtsE that mediate peptidoglycan hydrolysis by PcsB in Streptococcus pneumoniae.

Authors:  Ruchika Bajaj; Kevin E Bruce; Amy L Davidson; Britta E Rued; Cynthia V Stauffacher; Malcolm E Winkler
Journal:  Microbiologyopen       Date:  2016-05-10       Impact factor: 3.139

2.  Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.

Authors:  Britta E Rued; Martín Alcorlo; Katherine A Edmonds; Siseth Martínez-Caballero; Daniel Straume; Yue Fu; Kevin E Bruce; Hongwei Wu; Leiv S Håvarstein; Juan A Hermoso; Malcolm E Winkler; David P Giedroc
Journal:  mBio       Date:  2019-01-29       Impact factor: 7.867
  2 in total

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