A Zouak1, É Bongrain2, C Launois1, J Nardi1, J Vella-Boucaud1, G Deslee1, F Lebargy1, J-M Perotin3. 1. Service des maladies respiratoires et allergiques, centre hospitalier universitaire, 45, rue Cognacq-Jay, 51100 Reims, France. 2. Service de pneumologie, centre hospitalier, 51200 Épernay, France. 3. Service des maladies respiratoires et allergiques, centre hospitalier universitaire, 45, rue Cognacq-Jay, 51100 Reims, France. Electronic address: jmperotin-collard@chu-reims.fr.
Abstract
BACKGROUND: Eosinophilic pleural effusions are defined by an eosinophil count ≥10% in pleural fluid and represent approximately 10% of exudative pleural effusions. OBSERVATION: We report the first case of eosinophilic pleural effusion occurring due to lisinopril treatment. Improvement after drug discontinuation and recurrence after reintroduction indicated that lisinopril was responsible for the effusion. CONCLUSION: The main causes of eosinophilic pleural effusions are infections including tuberculosis, and malignancies. Drug-induced eosinophilic pleural effusions have only rarely been described, mainly caused by cardiovascular or neuropsychiatric medicines.
BACKGROUND:Eosinophilic pleural effusions are defined by an eosinophil count ≥10% in pleural fluid and represent approximately 10% of exudative pleural effusions. OBSERVATION: We report the first case of eosinophilic pleural effusion occurring due to lisinopril treatment. Improvement after drug discontinuation and recurrence after reintroduction indicated that lisinopril was responsible for the effusion. CONCLUSION: The main causes of eosinophilic pleural effusions are infections including tuberculosis, and malignancies. Drug-induced eosinophilic pleural effusions have only rarely been described, mainly caused by cardiovascular or neuropsychiatric medicines.