| Literature DB >> 26369436 |
Vicky Dritsou, Pantelis Topalis, Nikolai Windbichler, Alekos Simoni, Ann Hall, Daniel Lawson, Malcolm Hinsley, Daniel Hughes, Valerio Napolioni, Francesca Crucianelli, Elena Deligianni, Giuliano Gasperi, Ludvik M Gomulski, Grazia Savini, Mosè Manni, Francesca Scolari, Anna R Malacrida, Bruno Arcà, José M Ribeiro, Fabrizio Lombardo, Giuseppe Saccone, Marco Salvemini, Riccardo Moretti, Giuseppe Aprea, Maurizio Calvitti, Matteo Picciolini, Philippos Aris Papathanos, Roberta Spaccapelo, Guido Favia, Andrea Crisanti, Christos Louis.
Abstract
The draft genome sequence of Italian specimens of the Asian tiger mosquito Aedes (Stegomyia) albopictus (Diptera: Culicidae) was determined using a standard NGS (next generation sequencing) approach. The size of the assembled genome is comparable to that of Aedes aegypti; the two mosquitoes are also similar as far as the high content of repetitive DNA is concerned, most of which is made up of transposable elements. Although, based on BUSCO (Benchmarking Universal Single-Copy Orthologues) analysis, the genome assembly reported here contains more than 99% of protein-coding genes, several of those are expected to be represented in the assembly in a fragmented state. We also present here the annotation of several families of genes (tRNA genes, miRNA genes, the sialome, genes involved in chromatin condensation, sex determination genes, odorant binding proteins and odorant receptors). These analyses confirm that the assembly can be used for the study of the biology of this invasive vector of disease.Entities:
Keywords: BUSCO,; Chikungunya; Dengue fever,; Disease vector,; Invasive species,; NGS,; Repetitive DNA,; Transposable elements,; WGS,
Mesh：
Year: 2015 PMID： 26369436 PMCID： PMC4727573 DOI： 10.1179/2047773215Y.0000000031
Source DB: PubMed Journal: Pathog Glob Health ISSN： 2047-7724 Impact factor: 2.894