Literature DB >> 26366706

Vestibular Prostheses Investigated in Animal Models.

Richard F Lewis.   

Abstract

Loss of peripheral vestibular function results in debilitating postural, perceptual, and visual symptoms. A new approach to treating this clinical problem is to replace some aspects of peripheral vestibular function with a prosthesis that senses head motion and provides this information to the brain by stimulating the vestibular nerve. In this paper, I review studies done in animals over the past 15 years which lay the groundwork for transferring this approach to human patients with severe peripheral vestibular damage. The animal studies demonstrate that the visual and perceptual defects associated with peripheral vestibular damage can be improved with a vestibular implant, but the data on postural control remain less conclusive at this point in time.
© 2015 S. Karger AG, Basel.

Entities:  

Year:  2015        PMID: 26366706      PMCID: PMC4792791          DOI: 10.1159/000433551

Source DB:  PubMed          Journal:  ORL J Otorhinolaryngol Relat Spec        ISSN: 0301-1569            Impact factor:   1.538


  21 in total

1.  Prototype neural semicircular canal prosthesis using patterned electrical stimulation.

Authors:  W Gong; D M Merfeld
Journal:  Ann Biomed Eng       Date:  2000-05       Impact factor: 3.934

2.  Frequency dependence of vestibuloocular reflex thresholds.

Authors:  Csilla Haburcakova; Richard F Lewis; Daniel M Merfeld
Journal:  J Neurophysiol       Date:  2011-11-09       Impact factor: 2.714

3.  Auditory outcomes following implantation and electrical stimulation of the semicircular canals.

Authors:  Steven M Bierer; Leo Ling; Kaibao Nie; Albert F Fuchs; Chris R S Kaneko; Trey Oxford; Amy L Nowack; Sarah J Shepherd; Jay T Rubinstein; James O Phillips
Journal:  Hear Res       Date:  2012-04-05       Impact factor: 3.208

4.  Spatial and temporal properties of eye movements produced by electrical stimulation of semicircular canal afferents.

Authors:  Richard F Lewis; Csilla Haburcakova; Wangsong Gong; Faisal Karmali; Daniel M Merfeld
Journal:  J Neurophysiol       Date:  2012-06-06       Impact factor: 2.714

5.  Chronic vestibulo-ocular reflexes evoked by a vestibular prosthesis.

Authors:  Daniel M Merfeld; Csilla Haburcakova; Wangsong Gong; Richard F Lewis
Journal:  IEEE Trans Biomed Eng       Date:  2007-06       Impact factor: 4.538

6.  Vestibuloocular reflex adaptation investigated with chronic motion-modulated electrical stimulation of semicircular canal afferents.

Authors:  Richard F Lewis; Csilla Haburcakova; Wangsong Gong; Chadi Makary; Daniel M Merfeld
Journal:  J Neurophysiol       Date:  2009-12-16       Impact factor: 2.714

7.  Pseudospontaneous activity: stochastic independence of auditory nerve fibers with electrical stimulation.

Authors:  J T Rubinstein; B S Wilson; C C Finley; P J Abbas
Journal:  Hear Res       Date:  1999-01       Impact factor: 3.208

8.  Vestibular prosthesis tested in rhesus monkeys.

Authors:  Richard F Lewis; Csilla Haburcakova; Wangsong Gong; Daniel Lee; Conrad Wall; Lara Thompson; Daniel M Merfeld
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2011

9.  Vestibulo-ocular responses evoked via bilateral electrical stimulation of the lateral semicircular canals.

Authors:  Wangsong Gong; Csilla Haburcakova; Daniel M Merfeld
Journal:  IEEE Trans Biomed Eng       Date:  2008-11       Impact factor: 4.538

10.  System design and performance of a unilateral horizontal semicircular canal prosthesis.

Authors:  Wangsong Gong; Daniel M Merfeld
Journal:  IEEE Trans Biomed Eng       Date:  2002-02       Impact factor: 4.538

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  1 in total

1.  Recent Evidence About the Effectiveness of Vestibular Rehabilitation.

Authors:  Susan L Whitney; Ahmad H Alghadir; Shahnawaz Anwer
Journal:  Curr Treat Options Neurol       Date:  2016-03       Impact factor: 3.598

  1 in total

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