| Literature DB >> 26364836 |
H Sifuentes1, S Kane2.
Abstract
Multiple studies have demonstrated an increased risk for extra-intestinal cancers in inflammatory bowel disease (IBD) patients, mainly from treatment modalities. Prominent cancers that are related to IBD treatment include the following: lymphoproliferative disorders associated with thiopurine use, hepatosplenic T cell lymphoma primarily in younger male patients on thiopurines and anti-tumor necrosis factor (TNF) agents, non-melanoma skin cancers in patients treated with thiopurines and anti-TNF agents, and melanomas in patients who are on monotherapy with anti-TNF agents. In addition, women with IBD may have higher rates of cervical dysplasia and cervical cancer. The focus of this review is to provide a comprehensive overview on extra-intestinal cancers in IBD patients and how to monitor for these malignancies.Entities:
Keywords: Cervical cancer; Cervical dysplasia; Crohn’s disease; Extra-intestinal cancers; Hepatosplenic T cell lymphoma; Inflammatory bowel disease; Lymphoma; Lymphoproliferative disorders; Melanoma; Non-Hodgkin lymphoma; Non-melanoma skin cancer; Ulcerative colitis
Mesh:
Substances:
Year: 2015 PMID: 26364836 DOI: 10.1007/s11894-015-0467-8
Source DB: PubMed Journal: Curr Gastroenterol Rep ISSN: 1522-8037