Dilek Erdoğan Arı1, Arzu Yıldırım Ar2, Firdevs Karadoğan2, Yetkin Özcabı3, Ayşegül Koçoğlu2, Fatih Kılıç3, Fatma Nur Akgün2. 1. Anesthesiology and Reanimation Department, Fatih Sultan Mehmet Educational and Research Hospital, Istanbul, Turkey. Electronic address: dilekerdoganari@gmail.com. 2. Anesthesiology and Reanimation Department, Fatih Sultan Mehmet Educational and Research Hospital, Istanbul, Turkey. 3. General Surgery Department, Fatih Sultan Mehmet Educational and Research Hospital, Istanbul, Turkey.
Abstract
STUDY OBJECTIVE: To evaluate the effectiveness of 0.125% bupivacaine compared to 0.25% bupivacaine for ultrasound-guided transversus abdominis plane (TAP) block in patients undergoing open inguinal hernia repair. DESIGN: Randomized, double-blind study. SETTING: Educational and research hospital. PATIENTS: Forty adult patients of American Society of Anesthesiologists physical status I-III undergoing elective primary unilateral open inguinal hernia repair under spinal anesthesia. INTERVENTIONS: Patients in group I received 20 mL of 0.25% bupivacaine, whereas patients in group II received 20 mL of 0.125% bupivacaine for TAP block at the end of the surgery. MEASUREMENTS: Pain intensity was assessed at rest and during coughing using 10-cm visual analog scale score at 5, 15, 30, and 45 minutes and 1, 2, 4, 6, 12, and 24 hours after TAP block. Morphine consumption and time to first morphine requirement were recorded. MAIN RESULTS:Visual analog scale scores at rest and during coughing were not significantly different between groups at all time points measured. Twenty-four hours of morphine consumption (7.72±7.33 mg in group I and 6.06±5.20 mg in group II; P=.437) and time to first morphine requirement (182.35±125.16 minutes in group I and 143.21±87.28 minutes in group II; P=.332) were not different between groups. CONCLUSIONS: 0.125% Bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine for ultrasound-guided TAP block in patients undergoing open inguinal hernia repair.
RCT Entities:
STUDY OBJECTIVE: To evaluate the effectiveness of 0.125% bupivacaine compared to 0.25% bupivacaine for ultrasound-guided transversus abdominis plane (TAP) block in patients undergoing open inguinal hernia repair. DESIGN: Randomized, double-blind study. SETTING: Educational and research hospital. PATIENTS: Forty adult patients of American Society of Anesthesiologists physical status I-III undergoing elective primary unilateral open inguinal hernia repair under spinal anesthesia. INTERVENTIONS:Patients in group I received 20 mL of 0.25% bupivacaine, whereas patients in group II received 20 mL of 0.125% bupivacaine for TAP block at the end of the surgery. MEASUREMENTS: Pain intensity was assessed at rest and during coughing using 10-cm visual analog scale score at 5, 15, 30, and 45 minutes and 1, 2, 4, 6, 12, and 24 hours after TAP block. Morphine consumption and time to first morphine requirement were recorded. MAIN RESULTS: Visual analog scale scores at rest and during coughing were not significantly different between groups at all time points measured. Twenty-four hours of morphine consumption (7.72±7.33 mg in group I and 6.06±5.20 mg in group II; P=.437) and time to first morphine requirement (182.35±125.16 minutes in group I and 143.21±87.28 minutes in group II; P=.332) were not different between groups. CONCLUSIONS: 0.125% Bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine for ultrasound-guided TAP block in patients undergoing open inguinal hernia repair.