Literature DB >> 26363515

Invited commentary: limitations and usefulness of the metabolically healthy obesity phenotype.

Patrick T Bradshaw, June Stevens.   

Abstract

The fraction of the obese population who appear to be free of the metabolic abnormalities that usually accompany excess adiposity has garnered a great deal of attention recently. The so-called "metabolically healthy obesity" concept is thought to offer a refinement of the traditional obesity definitions that are based solely on anthropometry. The commentary by Rey-López et al. (Am J Epidemiol. 2015;182(9):737-741) in this issue of the Journal highlights several limitations of the "metabolically healthy obesity" concept and calls into question its usefulness as a public health metric. We discuss several of the issues raised by these authors and offer some perspective on why the utility of this concept remains unresolved.
© The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  metabolic syndrome; metabolically healthy obesity; obesity

Mesh:

Year:  2015        PMID: 26363515      PMCID: PMC4617297          DOI: 10.1093/aje/kwv178

Source DB:  PubMed          Journal:  Am J Epidemiol        ISSN: 0002-9262            Impact factor:   4.897


  23 in total

Review 1.  Beyond body mass index.

Authors:  A M Prentice; S A Jebb
Journal:  Obes Rev       Date:  2001-08       Impact factor: 9.213

2.  2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society.

Authors:  Michael D Jensen; Donna H Ryan; Caroline M Apovian; Jamy D Ard; Anthony G Comuzzie; Karen A Donato; Frank B Hu; Van S Hubbard; John M Jakicic; Robert F Kushner; Catherine M Loria; Barbara E Millen; Cathy A Nonas; F Xavier Pi-Sunyer; June Stevens; Victor J Stevens; Thomas A Wadden; Bruce M Wolfe; Susan Z Yanovski; Harmon S Jordan; Karima A Kendall; Linda J Lux; Roycelynn Mentor-Marcel; Laura C Morgan; Michael G Trisolini; Janusz Wnek; Jeffrey L Anderson; Jonathan L Halperin; Nancy M Albert; Biykem Bozkurt; Ralph G Brindis; Lesley H Curtis; David DeMets; Judith S Hochman; Richard J Kovacs; E Magnus Ohman; Susan J Pressler; Frank W Sellke; Win-Kuang Shen; Sidney C Smith; Gordon F Tomaselli
Journal:  Circulation       Date:  2013-11-12       Impact factor: 29.690

3.  Mediators of the effect of body mass index on coronary heart disease: decomposing direct and indirect effects.

Authors:  Yuan Lu; Kaveh Hajifathalian; Eric B Rimm; Majid Ezzati; Goodarz Danaei
Journal:  Epidemiology       Date:  2015-03       Impact factor: 4.822

Review 4.  The prevalence of metabolically healthy obesity: a systematic review and critical evaluation of the definitions used.

Authors:  J P Rey-López; L F de Rezende; M Pastor-Valero; B H Tess
Journal:  Obes Rev       Date:  2014-07-16       Impact factor: 9.213

5.  Metabolically-healthy obesity and coronary artery calcification.

Authors:  Yoosoo Chang; Bo-Kyoung Kim; Kyung Eun Yun; Juhee Cho; Yiyi Zhang; Sanjay Rampal; Di Zhao; Hyun-Suk Jung; Yuni Choi; Jiin Ahn; João A C Lima; Hocheol Shin; Eliseo Guallar; Seungho Ryu
Journal:  J Am Coll Cardiol       Date:  2014-04-30       Impact factor: 24.094

6.  Three-year weight change and cardiometabolic risk factors in obese and normal weight adults who are metabolically healthy: the atherosclerosis risk in communities study.

Authors:  Z Cui; K P Truesdale; P T Bradshaw; J Cai; J Stevens
Journal:  Int J Obes (Lond)       Date:  2015-04-14       Impact factor: 5.095

7.  Is the metabolically healthy obesity phenotype an irrelevant artifact for public health?

Authors:  Juan Pablo Rey-López; Leandro Fornias de Rezende; Thiago Hérick de Sá; Emmanuel Stamatakis
Journal:  Am J Epidemiol       Date:  2015-09-12       Impact factor: 4.897

8.  Obesity Paradox should not interfere with public health efforts.

Authors:  J Stevens; P T Bradshaw; K P Truesdale; M D Jensen
Journal:  Int J Obes (Lond)       Date:  2014-04-15       Impact factor: 5.095

9.  The natural course of healthy obesity over 20 years.

Authors:  Joshua A Bell; Mark Hamer; Séverine Sabia; Archana Singh-Manoux; G David Batty; Mika Kivimaki
Journal:  J Am Coll Cardiol       Date:  2015-01-06       Impact factor: 24.094

10.  Visceral abdominal fat accumulation predicts the conversion of metabolically healthy obese subjects to an unhealthy phenotype.

Authors:  Y-C Hwang; T Hayashi; W Y Fujimoto; S E Kahn; D L Leonetti; M J McNeely; E J Boyko
Journal:  Int J Obes (Lond)       Date:  2015-04-29       Impact factor: 5.095

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  5 in total

1.  The association between metabolic health, obesity phenotype and the risk of breast cancer.

Authors:  Yong-Moon Mark Park; Alexandra J White; Hazel B Nichols; Katie M O'Brien; Clarice R Weinberg; Dale P Sandler
Journal:  Int J Cancer       Date:  2017-03-28       Impact factor: 7.396

2.  Person-centred Obesity Care - Techniques, Thresholds, Tools and Targets.

Authors:  Sanjay Kalra; Nitin Kapoor; Sunil Kota; Sambit Das
Journal:  Eur Endocrinol       Date:  2020-02-04

3.  Metabolic phenotypes of obesity: frequency, correlates and change over time in a cohort of postmenopausal women.

Authors:  G C Kabat; W Y-Y Wu; J W Bea; C Chen; L Qi; M L Stefanick; R T Chlebowski; D S Lane; J Wactawski-Wende; S Wassertheil-Smoller; T E Rohan
Journal:  Int J Obes (Lond)       Date:  2016-10-17       Impact factor: 5.095

Review 4.  Obesity or obesities? Controversies on the association between body mass index and premature mortality.

Authors:  Ottavio Bosello; Maria Pia Donataccio; Massimo Cuzzolaro
Journal:  Eat Weight Disord       Date:  2016-06       Impact factor: 4.652

5.  Incidence of components of metabolic syndrome in the metabolically healthy obese over 9 years follow-up: the Atherosclerosis Risk In Communities study.

Authors:  P T Bradshaw; K R Reynolds; L E Wagenknecht; C E Ndumele; J Stevens
Journal:  Int J Obes (Lond)       Date:  2017-10-09       Impact factor: 5.095

  5 in total

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