Literature DB >> 26362998

Seek and Ye Shall Find: Subclonal Anaplastic Lymphoma Kinase Mutations.

Rani E George1.   

Abstract

Bellini and colleagues demonstrate the importance of next-generation sequencing to uncover subclonal anaplastic lymphoma kinase (ALK) mutations in neuroblastoma. Although the significance of these subclonal aberrations is not yet understood, deep sequencing could identify patients whose tumors may respond to ALK inhibitors. ©2015 American Association for Cancer Research.

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Year:  2015        PMID： 26362998      PMCID： PMC4631645          DOI： 10.1158/1078-0432.CCR-15-1397

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  12 in total

1.  Emergence of new ALK mutations at relapse of neuroblastoma.

Authors:  Gudrun Schleiermacher; Niloufar Javanmardi; Virginie Bernard; Quentin Leroy; Julie Cappo; Thomas Rio Frio; Gaelle Pierron; Eve Lapouble; Valérie Combaret; Frank Speleman; Bram de Wilde; Anna Djos; Ingrid Ora; Fredrik Hedborg; Catarina Träger; Britt-Marie Holmqvist; Jonas Abrahamsson; Michel Peuchmaur; Jean Michon; Isabelle Janoueix-Lerosey; Per Kogner; Olivier Delattre; Tommy Martinsson
Journal:  J Clin Oncol       Date:  2014-07-28       Impact factor: 44.544

2.  The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma.

Authors:  Teeara Berry; William Luther; Namrata Bhatnagar; Yann Jamin; Evon Poon; Takaomi Sanda; Desheng Pei; Bandana Sharma; Winston R Vetharoy; Albert Hallsworth; Zai Ahmad; Karen Barker; Lisa Moreau; Hannah Webber; Wenchao Wang; Qingsong Liu; Antonio Perez-Atayde; Scott Rodig; Nai-Kong Cheung; Florence Raynaud; Bengt Hallberg; Simon P Robinson; Nathanael S Gray; Andrew D J Pearson; Suzanne A Eccles; Louis Chesler; Rani E George
Journal:  Cancer Cell       Date:  2012-07-10       Impact factor: 31.743

Review 3.  Clonal evolution in cancer.

Authors:  Mel Greaves; Carlo C Maley
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

4.  Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification.

Authors:  Sara De Brouwer; Katleen De Preter; Candy Kumps; Piotr Zabrocki; Michaël Porcu; Ellen M Westerhout; Arjan Lakeman; Jo Vandesompele; Jasmien Hoebeeck; Tom Van Maerken; Anne De Paepe; Geneviève Laureys; Johannes H Schulte; Alexander Schramm; Caroline Van Den Broecke; Joëlle Vermeulen; Nadine Van Roy; Klaus Beiske; Marleen Renard; Rosa Noguera; Olivier Delattre; Isabelle Janoueix-Lerosey; Per Kogner; Tommy Martinsson; Akira Nakagawara; Miki Ohira; Huib Caron; Angelika Eggert; Jan Cools; Rogier Versteeg; Frank Speleman
Journal:  Clin Cancer Res       Date:  2010-08-18       Impact factor: 12.531

5.  Deep Sequencing Reveals Occurrence of Subclonal ALK Mutations in Neuroblastoma at Diagnosis.

Authors:  Angela Bellini; Virginie Bernard; Quentin Leroy; Thomas Rio Frio; Gaelle Pierron; Valérie Combaret; Eve Lapouble; Nathalie Clement; Herve Rubie; Estelle Thebaud; Pascal Chastagner; Anne Sophie Defachelles; Christophe Bergeron; Nimrod Buchbinder; Sophie Taque; Anne Auvrignon; Dominique Valteau-Couanet; Jean Michon; Isabelle Janoueix-Lerosey; Olivier Delattre; Gudrun Schleiermacher
Journal:  Clin Cancer Res       Date:  2015-06-09       Impact factor: 12.531

6.  Oncogenic mutations of ALK kinase in neuroblastoma.

Authors:  Yuyan Chen; Junko Takita; Young Lim Choi; Motohiro Kato; Miki Ohira; Masashi Sanada; Lili Wang; Manabu Soda; Akira Kikuchi; Takashi Igarashi; Akira Nakagawara; Yasuhide Hayashi; Hiroyuki Mano; Seishi Ogawa
Journal:  Nature       Date:  2008-10-16       Impact factor: 49.962

7.  Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.

Authors:  Isabelle Janoueix-Lerosey; Delphine Lequin; Laurence Brugières; Agnès Ribeiro; Loïc de Pontual; Valérie Combaret; Virginie Raynal; Alain Puisieux; Gudrun Schleiermacher; Gaëlle Pierron; Dominique Valteau-Couanet; Thierry Frebourg; Jean Michon; Stanislas Lyonnet; Jeanne Amiel; Olivier Delattre
Journal:  Nature       Date:  2008-10-16       Impact factor: 49.962

Review 8.  Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology.

Authors:  Bengt Hallberg; Ruth H Palmer
Journal:  Nat Rev Cancer       Date:  2013-10       Impact factor: 60.716

9.  Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.

Authors:  Michaela Angelika Ihle; Jana Fassunke; Katharina König; Inga Grünewald; Max Schlaak; Nicole Kreuzberg; Lothar Tietze; Hans-Ulrich Schildhaus; Reinhard Büttner; Sabine Merkelbach-Bruse
Journal:  BMC Cancer       Date:  2014-01-10       Impact factor: 4.430

10.  Activating mutations in ALK provide a therapeutic target in neuroblastoma.

Authors:  Rani E George; Takaomi Sanda; Megan Hanna; Stefan Fröhling; William Luther; Jianming Zhang; Yebin Ahn; Wenjun Zhou; Wendy B London; Patrick McGrady; Liquan Xue; Sergey Zozulya; Vlad E Gregor; Thomas R Webb; Nathanael S Gray; D Gary Gilliland; Lisa Diller; Heidi Greulich; Stephan W Morris; Matthew Meyerson; A Thomas Look
Journal:  Nature       Date:  2008-10-16       Impact factor: 49.962
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