Literature DB >> 26360546

Metabotropic Glutamate Receptor 2 Positive Allosteric Modulators: Closing the Gate on Drug Abuse?

Kari A Johnson1, David M Lovinger2.   

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Year:  2015        PMID： 26360546      PMCID： PMC5026223          DOI： 10.1016/j.biopsych.2015.07.008

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN： 0006-3223            Impact factor:   13.382


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  9 in total

Review 1.  The glutamate homeostasis hypothesis of addiction.

Authors:  Peter W Kalivas
Journal:  Nat Rev Neurosci       Date:  2009-07-01       Impact factor: 34.870

Review 2.  Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction.

Authors:  Khaled Moussawi; Peter W Kalivas
Journal:  Eur J Pharmacol       Date:  2010-04-02       Impact factor: 4.432

3.  Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model.

Authors:  Daniele Caprioli; Marco Venniro; Tamara Zeric; Xuan Li; Sweta Adhikary; Rajtarun Madangopal; Nathan J Marchant; Federica Lucantonio; Geoffrey Schoenbaum; Jennifer M Bossert; Yavin Shaham
Journal:  Biol Psychiatry       Date:  2015-02-23       Impact factor: 13.382

Review 4.  Development of allosteric modulators of GPCRs for treatment of CNS disorders.

Authors:  Hilary Highfield Nickols; P Jeffrey Conn
Journal:  Neurobiol Dis       Date:  2013-09-27       Impact factor: 5.996

5.  Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies.

Authors:  Hiba Salih; Ion Anghelescu; Iva Kezic; Vikash Sinha; Eef Hoeben; Luc Van Nueten; Heidi De Smedt; Peter De Boer
Journal:  J Psychopharmacol       Date:  2015-03-03       Impact factor: 4.153

6.  The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys.

Authors:  Zuzana Justinova; Leigh V Panlilio; Maria E Secci; Godfrey H Redhi; Charles W Schindler; Alan J Cross; Ladislav Mrzljak; Amy Medd; Yavin Shaham; Steven R Goldberg
Journal:  Biol Psychiatry       Date:  2015-02-07       Impact factor: 13.382

7.  Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence.

Authors:  Matthias E Liechti; Loic Lhuillier; Klemens Kaupmann; Athina Markou
Journal:  J Neurosci       Date:  2007-08-22       Impact factor: 6.167

8.  Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence.

Authors:  Marcus W Meinhardt; Anita C Hansson; Stephanie Perreau-Lenz; Christina Bauder-Wenz; Oliver Stählin; Markus Heilig; Clive Harper; Karla U Drescher; Rainer Spanagel; Wolfgang H Sommer
Journal:  J Neurosci       Date:  2013-02-13       Impact factor: 6.167

9.  Loss of metabotropic glutamate receptor 2 escalates alcohol consumption.

Authors:  Zhifeng Zhou; Camilla Karlsson; Tiebing Liang; Wei Xiong; Mitsuru Kimura; Jenica D Tapocik; Qiaoping Yuan; Estelle Barbier; Austin Feng; Meghan Flanigan; Eric Augier; Mary-Anne Enoch; Colin A Hodgkinson; Pei-Hong Shen; David M Lovinger; Howard J Edenberg; Markus Heilig; David Goldman
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-30       Impact factor: 11.205
  9 in total
  2 in total

Review 1.  Reprogramming of mPFC transcriptome and function in alcohol dependence.

Authors:  M Heilig; E Barbier; A L Johnstone; J Tapocik; M W Meinhardt; S Pfarr; C Wahlestedt; W H Sommer
Journal:  Genes Brain Behav       Date:  2016-11-24       Impact factor: 3.449

Review 2.  Identification of the Risk Genes Associated With Vulnerability to Addiction: Major Findings From Transgenic Animals.

Authors:  Chloe J Jordan; Zheng-Xiong Xi
Journal:  Front Neurosci       Date:  2022-01-12       Impact factor: 4.677
  2 in total

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