Literature DB >> 26359975

Releasing the Brakes on Cancer Immunotherapy.

Dan R Littman1.   

Abstract

This year's Lasker∼DeBakey Clinical Research Award goes to James Allison for discovering that antibody blockade of the T cell molecule CTLA-4 unleashes the body's immune response against malignant tumors. This has led to development of multiple "immune checkpoint therapies" that are prolonging and saving the lives of thousands of cancer patients.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26359975     DOI： 10.1016/j.cell.2015.08.038

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  36 in total

Review 1.  Harnessing the plasticity of CD4(+) T cells to treat immune-mediated disease.

Authors:  Michel DuPage; Jeffrey A Bluestone
Journal:  Nat Rev Immunol       Date:  2016-02-15       Impact factor: 53.106

Review 2.  Role of AHR and HIF-1α in Glioblastoma Metabolism.

Authors:  Galina Gabriely; Michael A Wheeler; Maisa C Takenaka; Francisco J Quintana
Journal:  Trends Endocrinol Metab       Date:  2017-03-16       Impact factor: 12.015

Review 3.  Trial watch: Immune checkpoint blockers for cancer therapy.

Authors:  Claire Vanpouille-Box; Claire Lhuillier; Lucillia Bezu; Fernando Aranda; Takahiro Yamazaki; Oliver Kepp; Jitka Fucikova; Radek Spisek; Sandra Demaria; Silvia C Formenti; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2017-08-31       Impact factor: 8.110

Review 4.  Single-Cell Genomics: Approaches and Utility in Immunology.

Authors:  Karlynn E Neu; Qingming Tang; Patrick C Wilson; Aly A Khan
Journal:  Trends Immunol       Date:  2017-01-13       Impact factor: 16.687

5.  Decreased expression of programmed death-1 on CD8+ effector memory T lymphocytes correlates with the pathogenesis of type 1 diabetes.

Authors:  Yimei Shan; Yinghong Kong; Yan Zhou; Jingjing Guo; Qiyun Shi; Sicheng Li; Heming Guo; Yiting Huang; Sisi Ding; Cuiping Liu; Lei Cao; Yun Huang; Chen Fang; Ji Hu
Journal:  Acta Diabetol       Date:  2021-04-23       Impact factor: 4.280

Review 6.  Naturalizing mouse models for immunology.

Authors:  Andrea L Graham
Journal:  Nat Immunol       Date:  2021-01-25       Impact factor: 25.606

7.  Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.

Authors:  Irena Kaplanov; Yaron Carmi; Rachel Kornetsky; Avishai Shemesh; Galina V Shurin; Michael R Shurin; Charles A Dinarello; Elena Voronov; Ron N Apte
Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-13       Impact factor: 11.205

8.  Clinical Importance of CD200 Expression in Colorectal Liver Metastasis.

Authors:  Yasuko Matsuo; Masayuki Sho; Takeo Nomi; Daisuke Hokuto; Takahiro Yoshikawa; Naoki Kamitani; Kota Nakamura; Yosuke Iwasa
Journal:  Ann Surg Oncol       Date:  2021-01-03       Impact factor: 5.344

Review 9.  Novel strategies in immune checkpoint inhibitor drug development: How far are we from the paradigm shift?

Authors:  Geoffrey Alan Watson; Jeffrey Doi; Aaron Richard Hansen; Anna Spreafico
Journal:  Br J Clin Pharmacol       Date:  2020-06-13       Impact factor: 4.335

Review 10.  Implications of the tumor immune microenvironment for staging and therapeutics.

Authors:  Janis M Taube; Jérôme Galon; Lynette M Sholl; Scott J Rodig; Tricia R Cottrell; Nicolas A Giraldo; Alexander S Baras; Sanjay S Patel; Robert A Anders; David L Rimm; Ashley Cimino-Mathews
Journal:  Mod Pathol       Date:  2017-12-01       Impact factor: 7.842
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