Literature DB >> 26359267

Orthostatic hypotension is associated with decreased cerebrospinal fluid levels of chromogranin A in early stage of Parkinson disease.

Michaela Kaiserova1, Hana Prikrylova Vranova2, Jan Galuszka3, David Stejskal4,5, Katerina Mensikova2, Jana Zapletalova6, Jan Mares2, Petr Kanovsky2.   

Abstract

An association between the CSF chromogranin A (CgA) and orthostatic blood pressure changes was investigated in 20 patients in the early stage of Parkinson disease (PD). There was a positive correlation between the CSF CgA and diastolic blood pressure change, when CSF CgA levels were lower in patients with orthostatic hypotension (OH). Decreased CSF CgA may be useful in predicting OH in the early stage of PD.

Entities:  

Keywords:  Cerebrospinal fluid; Chromogranin A; Orthostatic hypotension; Parkinson’s disease

Mesh：

Substances：

Year:  2015        PMID： 26359267     DOI： 10.1007/s10286-015-0302-1

Source DB:  PubMed          Journal:  Clin Auton Res        ISSN： 0959-9851            Impact factor:   4.435


  9 in total

1.  Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson's disease.

Authors:  Satoshi Orimo; Atsushi Takahashi; Toshiki Uchihara; Fumiaki Mori; Akiyoshi Kakita; Koichi Wakabayashi; Hitoshi Takahashi
Journal:  Brain Pathol       Date:  2007-01       Impact factor: 6.508

2.  The prevalence of symptomatic orthostatic hypotension in patients with Parkinson's disease and atypical parkinsonism.

Authors:  Ainhi D Ha; Caitlin H Brown; Michele K York; Joseph Jankovic
Journal:  Parkinsonism Relat Disord       Date:  2011-09       Impact factor: 4.891

3.  Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.

Authors:  Roy Freeman; Wouter Wieling; Felicia B Axelrod; David G Benditt; Eduardo Benarroch; Italo Biaggioni; William P Cheshire; Thomas Chelimsky; Pietro Cortelli; Christopher H Gibbons; David S Goldstein; Roger Hainsworth; Max J Hilz; Giris Jacob; Horacio Kaufmann; Jens Jordan; Lewis A Lipsitz; Benjamin D Levine; Phillip A Low; Christopher Mathias; Satish R Raj; David Robertson; Paola Sandroni; Irwin Schatz; Ron Schondorff; Julian M Stewart; J Gert van Dijk
Journal:  Clin Auton Res       Date:  2011-04       Impact factor: 4.435

4.  Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson's disease and other synucleinopathies.

Authors:  David S Goldstein; Courtney Holmes; Yehonatan Sharabi
Journal:  Brain       Date:  2012-03-26       Impact factor: 13.501

5.  Co-distribution patterns of chromogranin B-like immunoreactivity with chromogranin A and secretoneurin within the human brainstem.

Authors:  A Kato; K Kammen-Jolly; R Fischer-Colbie; C Humpel; A Schrott-Fischer; J Marksteiner
Journal:  Brain Res       Date:  2000-01-10       Impact factor: 3.252

Review 6.  The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease.

Authors:  W R Gibb; A J Lees
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-06       Impact factor: 10.154

Review 7.  Cardiovascular dysautonomia in Parkinson disease: from pathophysiology to pathogenesis.

Authors:  Samay Jain; David S Goldstein
Journal:  Neurobiol Dis       Date:  2011-11-04       Impact factor: 5.996

8.  Cerebrospinal fluid levels of chromogranin A in the treatment-naïve early stage Parkinson's disease: a pilot study.

Authors:  Michaela Kaiserová; Hana Přikrylová Vranová; David Stejskal; Kateřina Menšíková; Petr Kaňovský
Journal:  J Neural Transm (Vienna)       Date:  2013-04-16       Impact factor: 3.575

9.  Orthostatic hypotension as an early finding in Parkinson's disease.

Authors:  David S Goldstein
Journal:  Clin Auton Res       Date:  2006-02       Impact factor: 4.435
  9 in total
  1 in total

1.  Cerebrospinal Fluid Levels of Chromogranin A in Parkinson's Disease and Multiple System Atrophy.

Authors:  Michaela Kaiserova; Monika Chudackova; Katerina Mensikova; Miroslav Vastik; Sandra Kurcova; Hana Prikrylova Vranova; David Stejskal; Petr Kanovsky
Journal:  Brain Sci       Date:  2021-01-22
  1 in total

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