| Literature DB >> 26358187 |
Heesun Cheong1, Daniel J Klionsky2.
Abstract
Anticancer therapeutics aimed at the inhibition of mTORC1 activity shift metabolism to favor the degradation of extracellular proteins. Recently Thompson and colleagues demonstrated a novel regulatory mechanism whereby mTORC1 plays a distinct role as a key regulator of metabolism depending on the environmental nutrient status.Entities:
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Year: 2015 PMID： 26358187 PMCID： PMC4650624 DOI： 10.1038/cr.2015.107
Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617