Jaime Ruiz-Tovar1,2, Lorea Zubiaga3, Maria Diez3, Ana Murcia4, Evangelina Boix5, José Luis Muñoz6, Carolina Llavero7. 1. Bariatric Surgery Unit, University Hospital Rey Juan Carlos, Madrid, Spain. jruiztovar@gmail.com. 2. , Corazon de Maria, 64, 7J, 28002, Madrid, Spain. jruiztovar@gmail.com. 3. Department of Surgery, Bariatric Surgery Unit, General University Hospital Elche, Alicante, Spain. 4. Department of Pharmacy, Bariatric Surgery Unit, General University Hospital Elche, Alicante, Spain. 5. Department of Endocrinology, Bariatric Surgery Unit, General University Hospital Elche, Alicante, Spain. 6. Department of Anesthesiology, Bariatric Surgery Unit, General University Hospital Elche, Alicante, Spain. 7. Department of Surgical Nursery, Hospital Sureste, Madrid, Spain.
Abstract
BACKGROUND: Between 2 and 8 weeks before surgery, most bariatric surgery groups establish strict dietary treatments with a total caloric intake of less than 1,000 kcal/day in order to maximize weight loss during this period of time. METHODS: A prospective randomized clinical trial of all the patients undergoinglaparoscopic sleeve gastrectomy (LSG) was performed. Patients were randomly assigned into 3 groups: those patients receiving a preoperative regular diet of 900 kcal/day (group 1), those receiving a preoperative balanced energy high-protein formula (group 2) and those receiving preoperative Immunonutrition (group 3). Preoperative weight loss, postoperative pain, complications and analytical acute phase reactants were investigated. RESULTS:Sixty patients were included in the study, 20 in each group. Preoperative excess weight loss was 7.7 % in group 1, 12.3 % in group 2 and 15.3 % in group 3 (p = 0.014). Median postoperative pain was 3.5 in group 1, 3 in group 2 and 2 in group 3 (p = 0.048). C-reactive protein determined 24 h after surgery was significantly lower in group 3 than in the other groups. AST and ALT values were significantly lower in group 3 than in the other groups, without significant differences between groups 1 and 2. CONCLUSIONS: Preoperative diet with Immunonutrition formulas during 2 weeks achieves a greater preoperative weight loss, lower postoperative pain and lower values of CRP and liver enzymes than high-protein formulas or regular diet, all of them with similar caloric intake.
RCT Entities:
BACKGROUND: Between 2 and 8 weeks before surgery, most bariatric surgery groups establish strict dietary treatments with a total caloric intake of less than 1,000 kcal/day in order to maximize weight loss during this period of time. METHODS: A prospective randomized clinical trial of all the patients undergoing laparoscopic sleeve gastrectomy (LSG) was performed. Patients were randomly assigned into 3 groups: those patients receiving a preoperative regular diet of 900 kcal/day (group 1), those receiving a preoperative balanced energy high-protein formula (group 2) and those receiving preoperative Immunonutrition (group 3). Preoperative weight loss, postoperative pain, complications and analytical acute phase reactants were investigated. RESULTS: Sixty patients were included in the study, 20 in each group. Preoperative excess weight loss was 7.7 % in group 1, 12.3 % in group 2 and 15.3 % in group 3 (p = 0.014). Median postoperative pain was 3.5 in group 1, 3 in group 2 and 2 in group 3 (p = 0.048). C-reactive protein determined 24 h after surgery was significantly lower in group 3 than in the other groups. AST and ALT values were significantly lower in group 3 than in the other groups, without significant differences between groups 1 and 2. CONCLUSIONS: Preoperative diet with Immunonutrition formulas during 2 weeks achieves a greater preoperative weight loss, lower postoperative pain and lower values of CRP and liver enzymes than high-protein formulas or regular diet, all of them with similar caloric intake.
Authors: M A Carbajo; Maria J Castro; S Kleinfinger; S Gómez-Arenas; J Ortiz-Solórzano; R Wellman; C García-Ianza; E Luque Journal: Nutr Hosp Date: 2010 Nov-Dec Impact factor: 1.057
Authors: T R Ziegler; L S Young; K Benfell; M Scheltinga; K Hortos; R Bye; F D Morrow; D O Jacobs; R J Smith; J H Antin Journal: Ann Intern Med Date: 1992-05-15 Impact factor: 25.391