Literature DB >> 26358064

A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms.

Nana Brochmann1, Ann-Dorthe Zwisler2, Mette Kjerholt3, Esben Meulengracht Flachs4, Hans Carl Hasselbalch3, Christen Lykkegaard Andersen3.   

Abstract

PURPOSE: An Internet-based tool for reporting and analysing patient-reported outcomes (PROs) has been developed. The tool enables merging PROs with blood test results and allows for computation of treatment responses. Data may be visualized by graphical analysis and may be exported for downstream statistical processing. The aim of this study was to investigate, whether patients with myeloproliferative neoplasms (MPNs) were willing and able to use the tool and fill out questionnaires regularly.
METHODS: Participants were recruited from the outpatient clinic at the Department of Haematology, Roskilde University Hospital, Denmark. Validated questionnaires that were used were European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30, Myeloproliferative Neoplasm Symptom Assessment Form, Brief Fatigue Inventory and Short Form 36 Health Survey. Questionnaires were filled out ≥ 6 months online or on paper according to participant preference. Regularity of questionnaire submission was investigated, and participant acceptance was evaluated by focus-group interviews.
RESULTS: Of 135 invited patients, 118 (87 %) accepted participation. One hundred and seven participants (91 %) preferred to use the Internet-based tool. Of the 118 enrolled participants, 104 (88 %) submitted PROs regularly ≥ 6 months. The focus-group interviews revealed that the Internet-based tool was well accepted.
CONCLUSION: The Internet-based approach and regular collection of PROs are well accepted with a high participation rate, persistency and adherence in a population of MPN patients. The plasticity of the platform allows for adaptation to patients with other medical conditions.

Entities:  

Keywords:  Feasibility study; Health-related quality of life; Internet-based tool; Myeloproliferative neoplasm; Patient-reported outcomes; Regular collection of patient-reported outcomes

Mesh:

Year:  2015        PMID: 26358064     DOI: 10.1007/s11136-015-1125-1

Source DB:  PubMed          Journal:  Qual Life Res        ISSN: 0962-9343            Impact factor:   4.147


  25 in total

1.  The qualitative content analysis process.

Authors:  Satu Elo; Helvi Kyngäs
Journal:  J Adv Nurs       Date:  2008-04       Impact factor: 3.187

2.  Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.

Authors:  Tiziano Barbui; Giovanni Barosi; Gunnar Birgegard; Francisco Cervantes; Guido Finazzi; Martin Griesshammer; Claire Harrison; Hans Carl Hasselbalch; Rudiger Hehlmann; Ronald Hoffman; Jean-Jacques Kiladjian; Nicolaus Kröger; Ruben Mesa; Mary F McMullin; Animesh Pardanani; Francesco Passamonti; Alessandro M Vannucchi; Andreas Reiter; Richard T Silver; Srdan Verstovsek; Ayalew Tefferi
Journal:  J Clin Oncol       Date:  2011-01-04       Impact factor: 44.544

3.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

Authors:  M E Charlson; P Pompei; K L Ales; C R MacKenzie
Journal:  J Chronic Dis       Date:  1987

Review 4.  The role of informatics in promoting patient-centered care.

Authors:  Claire F Snyder; Albert W Wu; Robert S Miller; Roxanne E Jensen; Elissa T Bantug; Antonio C Wolff
Journal:  Cancer J       Date:  2011 Jul-Aug       Impact factor: 3.360

5.  The Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF): international prospective validation and reliability trial in 402 patients.

Authors:  Robyn Scherber; Amylou C Dueck; Peter Johansson; Tiziano Barbui; Giovanni Barosi; Alessandro M Vannucchi; Francesco Passamonti; Bjorn Andreasson; Maria L Ferarri; Alessandro Rambaldi; Jan Samuelsson; Gunnar Birgegard; Ayalew Tefferi; Claire N Harrison; Deepti Radia; Ruben A Mesa
Journal:  Blood       Date:  2011-05-02       Impact factor: 22.113

6.  Gene expression profiling with principal component analysis depicts the biological continuum from essential thrombocythemia over polycythemia vera to myelofibrosis.

Authors:  Vibe Skov; Mads Thomassen; Caroline H Riley; Morten K Jensen; Ole Weis Bjerrum; Torben A Kruse; Hans Carl Hasselbalch; Thomas Stauffer Larsen
Journal:  Exp Hematol       Date:  2012-06-01       Impact factor: 3.084

7.  The burden of fatigue and quality of life in myeloproliferative disorders (MPDs): an international Internet-based survey of 1179 MPD patients.

Authors:  Ruben A Mesa; Joyce Niblack; Martha Wadleigh; Srdan Verstovsek; John Camoriano; Sunni Barnes; Angelina D Tan; Pamela J Atherton; Jeff A Sloan; Ayalew Tefferi
Journal:  Cancer       Date:  2007-01-01       Impact factor: 6.860

8.  Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms.

Authors:  Hans C Hasselbalch
Journal:  Expert Rev Hematol       Date:  2014-02-13       Impact factor: 2.929

9.  Prognostic value of quality of life scores in a trial of chemotherapy with or without interferon in patients with metastatic malignant melanoma.

Authors:  A Coates; D Thomson; G R McLeod; P Hersey; P G Gill; I N Olver; R Kefford; R M Lowenthal; G Beadle; E Walpole
Journal:  Eur J Cancer       Date:  1993       Impact factor: 9.162

10.  Use of Patient-Reported Outcome (PRO) Measures at Group and Patient Levels: Experiences From the Generic Integrated PRO System, WestChronic.

Authors:  Niels Henrik Ingvar Hjollund; Louise Pape Larsen; Karin Biering; Soren Paaske Johnsen; Erik Riiskjær; Liv Marit Schougaard
Journal:  Interact J Med Res       Date:  2014-02-11
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  1 in total

Review 1.  Acceptance and Use of Home-Based Electronic Symptom Self-Reporting Systems in Patients With Cancer: Systematic Review.

Authors:  Youmin Cho; Yun Jiang; Huiting Zhang; Marcelline Ruth Harris; Yang Gong; Ellen Lavoie Smith
Journal:  J Med Internet Res       Date:  2021-03-12       Impact factor: 5.428

  1 in total

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