Paul Brunault1,2,3, Anne-Laure Champagne1, Grégoire Huguet1, Isabelle Suzanne1, Jean-Louis Senon4, Gilles Body5, Emmanuel Rusch6, Guillaume Magnin7, Mélanie Voyer4, Christian Réveillère3, Vincent Camus1,8,9. 1. Clinique Psychiatrique Universitaire, CHRU de Tours, Tours, France. 2. Équipe de Liaison et de Soins en Addictologie, CHRU de Tours, Tours, France. 3. Département de Psychologie, EA 2114 Psychologie des Âges de la Vie, Université François Rabelais de Tours, Tours, France. 4. Centre Hospitalier Henri-Laborit, Service de Psychiatrie, Poitiers, France. 5. Service de Gynécologie Obstétrique, CHRU de Tours, Tours, France. 6. Service d'Information Médicale, Épidémiologie et Économie de la Santé, CHRU de Tours, Tours, France. 7. Service de Gynécologie Obstétrique, CHU de Poitiers, Poitiers, France. 8. UMR INSERM U930 'Imagerie et Cerveau', Tours, France. 9. Université François Rabelais de Tours, Tours, France.
Abstract
OBJECTIVE: Our aim was to identify risk factors for lower quality of life (QOL) in non-metastatic breast cancer patients. METHODS: Our study included 120 patients from the University Hospital Centers of Tours and Poitiers. This cross-sectional study was conducted 7 months after patients' breast cancer diagnosis and assessed QOL (Quality of Life Questionnaire Core 30 = QLQ-C30), socio-demographic characteristics, coping strategies (Brief-COPE), physiological and biological variables (e.g., initial tumor severity and types of treatment received), the existence of major depressive disorder (Mini International Neuropsychiatric Interview), and pain severity (Questionnaire de Douleur Saint Antoine). We assessed personality disorders 3 months after diagnosis (Vragenlijst voor Kenmerken van de Persoonlijkheid questionnaire). We used multiple linear regression models to determine which factors were associated with physical, emotional, and global QOL. RESULTS: Lower physical QOL was associated with major depressive disorder, younger age, a more severe initial tumor stage, and the use of the behavioral disengagement coping. Lower emotional QOL was associated with major depressive disorder, the existence of a personality disorder, a more severe pain level, higher use of self-blame, and lower use of acceptance coping strategies. Lower global QOL was associated with major depressive disorder, the existence of a personality disorder, a more severe pain level, higher use of self-blame, lower use of positive reframing coping strategies, and an absence of hormone therapy. CONCLUSIONS: Lower QOL scores were more strongly associated with variables related to the individual's premorbid psychological characteristics and the manner in which this individual copes with the cancer (e.g., depression, personality, and coping) than to cancer-related variables (e.g., treatment types and cancer severity).
OBJECTIVE: Our aim was to identify risk factors for lower quality of life (QOL) in non-metastatic breast cancerpatients. METHODS: Our study included 120 patients from the University Hospital Centers of Tours and Poitiers. This cross-sectional study was conducted 7 months after patients' breast cancer diagnosis and assessed QOL (Quality of Life Questionnaire Core 30 = QLQ-C30), socio-demographic characteristics, coping strategies (Brief-COPE), physiological and biological variables (e.g., initial tumor severity and types of treatment received), the existence of major depressive disorder (Mini International Neuropsychiatric Interview), and pain severity (Questionnaire de Douleur Saint Antoine). We assessed personality disorders 3 months after diagnosis (Vragenlijst voor Kenmerken van de Persoonlijkheid questionnaire). We used multiple linear regression models to determine which factors were associated with physical, emotional, and global QOL. RESULTS: Lower physical QOL was associated with major depressive disorder, younger age, a more severe initial tumor stage, and the use of the behavioral disengagement coping. Lower emotional QOL was associated with major depressive disorder, the existence of a personality disorder, a more severe pain level, higher use of self-blame, and lower use of acceptance coping strategies. Lower global QOL was associated with major depressive disorder, the existence of a personality disorder, a more severe pain level, higher use of self-blame, lower use of positive reframing coping strategies, and an absence of hormone therapy. CONCLUSIONS: Lower QOL scores were more strongly associated with variables related to the individual's premorbid psychological characteristics and the manner in which this individual copes with the cancer (e.g., depression, personality, and coping) than to cancer-related variables (e.g., treatment types and cancer severity).
Authors: Ryan D Nipp; Areej El-Jawahri; Joel N Fishbein; Justin Eusebio; Jamie M Stagl; Emily R Gallagher; Elyse R Park; Vicki A Jackson; William F Pirl; Joseph A Greer; Jennifer S Temel Journal: Cancer Date: 2016-04-18 Impact factor: 6.860
Authors: Ryan D Nipp; Joseph A Greer; Areej El-Jawahri; Samantha M Moran; Lara Traeger; Jamie M Jacobs; Juliet C Jacobsen; Emily R Gallagher; Elyse R Park; David P Ryan; Vicki A Jackson; William F Pirl; Jennifer S Temel Journal: J Clin Oncol Date: 2017-06-02 Impact factor: 44.544
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Authors: Sarah D Kowitt; Katrina R Ellis; Veronica Carlisle; Nivedita L Bhushan; Kristin Z Black; Kaitlyn Brodar; Nicole M Cranley; Kia L Davis; Eugenia Eng; Michelle Y Martin; Jared McGuirt; Rebeccah L Sokol; Patrick Y Tang; Anissa I Vines; Jennifer S Walker; Edwin B Fisher Journal: Support Care Cancer Date: 2018-10-06 Impact factor: 3.603
Authors: Molly E Ream; Mollie S Pester; Zachary T Goodman; Sierra A Bainter; Michael H Antoni Journal: Psychooncology Date: 2020-12-21 Impact factor: 3.894